Grant: Collaborative Health Research Projects
University of British Columbia
$308,571.00
Development of an automated end-to-end next generation sequencing assay to detect all classes of genetic variant in a single diagnostic test
FY 2017-18
Summary
Each year more than 190,000 Canadians are diagnosed with cancer and about 77,000 die from the disease. Genetic testingof tumor tissue is required for most types of cancer to help make a diagnosis and to choose treatments. New methods arenow being developed that can test blood to detect genetic changes in the tumor. Blood tests would avoid surgery, may becheaper and might be useful for following the size of a patients tumor. The aim of this project is to create an automatedsingle genetic test that will be able to detect many cancer genetic changes at once, and can be used either on the tumortissue or on blood. The test will be used to help make a diagnosis, and also possibly to monitor whether a patient isresponding to treatment, or whether the cancer has returned. We will work with physicians at the BC Cancer Agency tomake the reporting of the test results quick and convenient, and determine how this new test would change the managementof cancer patients. We expect the test will be used in several provinces and research groups through our clinical testinglaboratory, and help improve the management of cancer patients.
Program
Collaborative Health Research Projects
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
493628-2016
Name nom
Karsan, Aly
Department département
Pathology and Lab Medicine
Organization id
2
Institution établissement
University of British Columbia
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2017
Competition year année de concours
2016
Award amount
308571
Program id
CHRPJ
Program name en
Collaborative Health Research Projects
Program name fr
Projets de recherche concertée sur la santé
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
360
Committee name en
Collaborative Health Research Projects Selection Panel
Committee name fr
Comité de sélection de projets de recherche concertée sur la santé
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
9999
Research subject group en
Not available
Research subject group fr
Non disponible
Research subject en
Not available
Research subject fr
Non disponible
Partie
2 & 3
Nb partie
3
Application title
Development of an automated end-to-end next generation sequencing assay to detect all classes of genetic variant in a single diagnostic test
Keyword
NSERC
Application summary
Each year more than 190,000 Canadians are diagnosed with cancer and about 77,000 die from the disease. Genetic testingof tumor tissue is required for most types of cancer to help make a diagnosis and to choose treatments. New methods arenow being developed that can test blood to detect genetic changes in the tumor. Blood tests would avoid surgery, may becheaper and might be useful for following the size of a patients tumor. The aim of this project is to create an automatedsingle genetic test that will be able to detect many cancer genetic changes at once, and can be used either on the tumortissue or on blood. The test will be used to help make a diagnosis, and also possibly to monitor whether a patient isresponding to treatment, or whether the cancer has returned. We will work with physicians at the BC Cancer Agency tomake the reporting of the test results quick and convenient, and determine how this new test would change the managementof cancer patients. We expect the test will be used in several provinces and research groups through our clinical testinglaboratory, and help improve the management of cancer patients.
