Grant: Early Career Investigator Awards - Hypertension
University of Alberta
$245,000.00
Hypertension in Small Vessel Lacunar Stroke
FY 2017-18
Summary
Hypertension is a common cause small vessel stroke. We have no specific treatments for hypertension small vessel stroke and limited understanding regarding its cause in humans. This study will evaluate immune activation by hypertension that promotes small vessel injury and lacunar stroke. Differences in hypertensive injury compared to injury from diabetes and hyperlipidemia will be assessed. Hypertensive immune activation that promotes lacunar stroke may identify novel targets to treat and prevent cerebral small vessel disease.
Department
Program
Early Career Investigator Awards - Hypertension
Recipient
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
373153
Name
Jickling Glen
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Hypertension Canada (Markham, Ontario); Hypertension Canada (Markham, Ontario)
Instname2
Circulatory and Respiratory Health
Theme2
Clinical
Prcname2
Early Career Investigator Awards (clinician)
Projecttitle
Hypertension in Small Vessel Lacunar Stroke
Programtype2
Salary Programs
Orgnameinp2
University of Alberta
Cihramount2
$245,000
Cihrequipment2
$0
Programname2
Early Career Investigator Awards - Hypertension
Keyworddelim
Blood Brain Barrier; Cerebral Small Vessel Disease; Chemokine; Ischemic Stroke; Lacunar Stroke; Leukocyte Biology
Abstract
Hypertension is a common cause small vessel stroke. We have no specific treatments for hypertension small vessel stroke and limited understanding regarding its cause in humans. This study will evaluate immune activation by hypertension that promotes small vessel injury and lacunar stroke. Differences in hypertensive injury compared to injury from diabetes and hyperlipidemia will be assessed. Hypertensive immune activation that promotes lacunar stroke may identify novel targets to treat and prevent cerebral small vessel disease.
Competitiondate
201709
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Jickling, Glen
Approvedterm
3 ans 0 mois
Cihrcontribution2
Inst of Circ &Respiratory Hlth~ $245,000~ $0~
