Grant: Doctoral Research Award: Canada Graduate Scholarships
Centre for Addiction and Mental Health (Toronto)
$105,000.00
A Data-Driven Approach to Identifying Therapeutic Targets for Negative Symptoms in Schizophrenia
FY 2019-20
Summary
With a prevalence rate of approximately 1%, schizophrenia affects a large proportion of Canadians and is associated with a tremendous burden for the individual, their family, and society at large. Estimates of the economic costs of schizophrenia in Canada suggest that total yearly costs associated with this illness are $6.85 billion, with 70% of this attributable to lost productivity. Negative symptoms - referring to decreases in motivation, interest, and emotional expression - are a critical determinant of this functional disability for individuals with schizophrenia, for which there are currently no effective psychopharmacological treatments. With increasing research suggesting the need for complementary psychotherapeutic interventions, this study aims to evaluate the specific psychological processes contributing to negative symptoms over time in order to uncover precise targets for these treatments. The results of this study are anticipated to provide the foundation for the development of personalized psychological interventions for negative symptoms in schizophrenia to address the critical area of unmet therapeutic need and promote recovery for these individuals.
Department
Program
Doctoral Research Award: Canada Graduate Scholarships
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
416895
Name
Saperia Sarah
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Clinical
Prcname2
Doctoral Research Awards - A
Projecttitle
A Data-Driven Approach to Identifying Therapeutic Targets for Negative Symptoms in Schizophrenia
Programtype2
Studentship Programs
Orgnameinp2
Centre for Addiction and Mental Health (Toronto)
Cihramount2
$105,000
Cihrequipment2
$0
Programname2
Doctoral Research Award: Canada Graduate Scholarships
Keyworddelim
Negative Symptoms; Psychological Interventions; Schizophrenia; Treatment Targets
Abstract
With a prevalence rate of approximately 1%, schizophrenia affects a large proportion of Canadians and is associated with a tremendous burden for the individual, their family, and society at large. Estimates of the economic costs of schizophrenia in Canada suggest that total yearly costs associated with this illness are $6.85 billion, with 70% of this attributable to lost productivity. Negative symptoms - referring to decreases in motivation, interest, and emotional expression - are a critical determinant of this functional disability for individuals with schizophrenia, for which there are currently no effective psychopharmacological treatments. With increasing research suggesting the need for complementary psychotherapeutic interventions, this study aims to evaluate the specific psychological processes contributing to negative symptoms over time in order to uncover precise targets for these treatments. The results of this study are anticipated to provide the foundation for the development of personalized psychological interventions for negative symptoms in schizophrenia to address the critical area of unmet therapeutic need and promote recovery for these individuals.
Competitiondate
201911
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Saperia, Sarah
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $105,000~ $0~