Grant: CIHR Fellowship
University of British Columbia
$135,000.00
The role of the airway epithelium inflammasome in asthma pathogenesis
FY 2009-10
Summary
Asthma is a world-wide respiratory disease that affects more than 300 million individuals and causes considerable burden on health care systems due to direct (medicare and drugs) and indirect (mortality, quality of life, lost productivity in workplace)costs. The airway epithelium is the first line of defense against inhaled allergens, viruses, bacteria, and environmental pollutants. Recently the airway epithelium in asthmatics has been shown to different from non-asthmatics in it's ability to repair itself. Understanding the mechanisms underlying why asthmatic epithelium and it's repair processes differ from non-asthmatics will provide insight into disease development and shed light on new therapeutic options.
Department
Program
CIHR Fellowship
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
202994
Name
Hirota Jeremy A
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Fellowships - Post-PhD
Projecttitle
The role of the airway epithelium inflammasome in asthma pathogenesis
Programtype2
Fellowship Programs
Orgnameinp2
University of British Columbia
Cihramount2
$135,000
Cihrequipment2
$0
Programname2
CIHR Fellowship
Keyworddelim
Asthma; Epithelial Mesenchymal Transition; Epithelium; Growth Factors; Inflammasome; Mouse; Repair; Transgenics
Abstract
Asthma is a world-wide respiratory disease that affects more than 300 million individuals and causes considerable burden on health care systems due to direct (medicare and drugs) and indirect (mortality, quality of life, lost productivity in workplace)costs. The airway epithelium is the first line of defense against inhaled allergens, viruses, bacteria, and environmental pollutants. Recently the airway epithelium in asthmatics has been shown to different from non-asthmatics in it's ability to repair itself. Understanding the mechanisms underlying why asthmatic epithelium and it's repair processes differ from non-asthmatics will provide insight into disease development and shed light on new therapeutic options.
Competitiondate
201002
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Hirota, Jeremy A
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $135,000~ $0~
