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Grant: Project Grant

McGill University

$1,005,316.00

The PREvention Program for Alzheimer's RElated Delirium (PREPARED) Cluster Randomized Trial

FY 2015-16

Summary
By the year 2038, over a million Canadians are expected to have Alzheimer's disease, a type of dementia. Dementia increases the risk of nursing home placement among the elderly more than fivefold. Given the exceptionally vulnerable nature of this patient population, there is a pressing need to ensure that the clinical care they receive is evidence-based, tailored specifically for them, and meeting the high standards of quality that would be expected in any other health-care setting. Delirium is a sudden and severe change in brain function that can cause a person to appear confused or disoriented, have memory loss, and have difficulties maintaining focus. It is an urgent care issue facing elderly patients residing in nursing homes, or long-term care (LTC) facilities. Delirium is a significant cause of illness and mortality, affecting between 10%-89% of LTC patients, but little research has focused on delirium prevention in the LTC setting. This study will assess the effectiveness of a LTC Multicomponent Delirium Prevention Program (MDPP). The MDPP is an educational intervention provided to nursing staff working in LTC facilities that consists of four components: a decision tree, an instruction manual, a training package, and a toolkit. The feasibility and acceptability of the MDPP has already been successfully demonstrated; however, a thorough and well-designed large scale study is needed in order to confirm its ability to reduce delirium among LTC residents. In this study, at least 16 LTC facilities will be randomized to either receive the MDPP or to receive usual care. At the end of the 4-year study period, we will be able to demonstrate the degree to which the MDPP intervention reduces: 1) the number of new cases of delirium; 2) delirium severity; and 3) the duration of delirium episodes. This study will provide the blueprint of a program that can be transferable to LTC institutions across Canada.
Program
Project Grant
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
346562
Name
Wilchesky Machelle
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Population and Public Health
Theme2
Clinical
Prcname2
Project Grant Competition
Projecttitle
The PREvention Program for Alzheimer's RElated Delirium (PREPARED) Cluster Randomized Trial
Programtype2
Operating Grants
Orgnameinp2
McGill University
Cihramount2
$1,005,316
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Cluster-Randomized Trial; Delirium; Dementia; Long-Term Care; Nursing; Prevention Program
Abstract
By the year 2038, over a million Canadians are expected to have Alzheimer's disease, a type of dementia. Dementia increases the risk of nursing home placement among the elderly more than fivefold. Given the exceptionally vulnerable nature of this patient population, there is a pressing need to ensure that the clinical care they receive is evidence-based, tailored specifically for them, and meeting the high standards of quality that would be expected in any other health-care setting. Delirium is a sudden and severe change in brain function that can cause a person to appear confused or disoriented, have memory loss, and have difficulties maintaining focus. It is an urgent care issue facing elderly patients residing in nursing homes, or long-term care (LTC) facilities. Delirium is a significant cause of illness and mortality, affecting between 10%-89% of LTC patients, but little research has focused on delirium prevention in the LTC setting. This study will assess the effectiveness of a LTC Multicomponent Delirium Prevention Program (MDPP). The MDPP is an educational intervention provided to nursing staff working in LTC facilities that consists of four components: a decision tree, an instruction manual, a training package, and a toolkit. The feasibility and acceptability of the MDPP has already been successfully demonstrated; however, a thorough and well-designed large scale study is needed in order to confirm its ability to reduce delirium among LTC residents. In this study, at least 16 LTC facilities will be randomized to either receive the MDPP or to receive usual care. At the end of the 4-year study period, we will be able to demonstrate the degree to which the MDPP intervention reduces: 1) the number of new cases of delirium; 2) delirium severity; and 3) the duration of delirium episodes. This study will provide the blueprint of a program that can be transferable to LTC institutions across Canada.
Competitiondate
201603
Approvedterm2
4 yrs 0 mth
Pinamesdelim
Wilchesky, Machelle
Approvedterm
4 ans 0 mois
Cihrcontribution2
~ $1,005,316~ $0~