Grant: Canada Research Chairs
Simon Fraser University
$120,000.00
Functional RNA and Cellular Stress
FY 2020-21
Summary
Cells must adapt to changing environmental conditions in order to survive. Interestingly, an emerging class of biological molecules (noncoding RNA) have recently been shown to be essential to many of these responsive pathways. Dr. Audas laboratory will study the role of noncoding RNA in the stress-induced conversion of proteins to a new type of natural protein aggregate. He intends to identify regulators, protein targets, and cellular consequences associated with this pathway, enhancing our understanding of cellular adaptability. Research outcomes will also impact the study of aggregate-based neurological diseases, generating new avenues to combat conditions affecting Canadas aging population.
Program
Canada Research Chairs
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
1000231410
Name nom
Audas, Timothy
Department département
Molecular Biology and Biochemistry
Organization id
5
Institution établissement
Simon Fraser University
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2020
Competition year année de concours
2016
Award amount
120000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
5300
Research subject group en
Molecular biology
Research subject group fr
Biologie moléculaire
Research subject en
Molecular biology
Research subject fr
Biologie moléculaire
Partie
0
Nb partie
0
Application title
Functional RNA and Cellular Stress
Keyword
NSERC
Application summary
Cells must adapt to changing environmental conditions in order to survive. Interestingly, an emerging class of biological molecules (noncoding RNA) have recently been shown to be essential to many of these responsive pathways. Dr. Audas laboratory will study the role of noncoding RNA in the stress-induced conversion of proteins to a new type of natural protein aggregate. He intends to identify regulators, protein targets, and cellular consequences associated with this pathway, enhancing our understanding of cellular adaptability. Research outcomes will also impact the study of aggregate-based neurological diseases, generating new avenues to combat conditions affecting Canadas aging population.
