Grant: Canada Research Chairs
York University
$150,000.00
Cell Physiology
FY 2023-24
Summary
Professor Hood¿s research program is aimed at investigating the role of exercise in enhancing the synthesis of mitochondria, the cellular organelles responsible for energy production, with a focus on skeletal muscle. Combining an analysis of mitochondrial biology with exercise physiology, Hood¿s studies allow us to understand the role of regular exercise in reversing mitochondrial dysfunction and cell death which occur during the normal process of aging, as well as in metabolic disorders such as diabetes and obesity. This research will have important implications for our understanding of the value of exercise in improving metabolic health, and in rejuvenating aging muscle.
Program
Canada Research Chairs
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
CRC-2016-00077
Name nom
Hood, David
Department département
Muscle Health Research Centre - York University
Organization id
38
Institution établissement
York University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2016
Award amount
150000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
10000
Research subject group en
The field of research available
Research subject group fr
The field of research available
Research subject en
Le domaine de recherche disponible
Research subject fr
Le domaine de recherche disponible
Field of research list codes
RDF301
Field of research list names en
Basic medicine and life sciences
Field of research list names fr
Médecine fondamentale et sciences de la vie
Application title
Cell Physiology
Keyword
Skeletal muscle
mitochondria
gene expression
exercise
autophagy
muscle adaptations
muscle health
transcriptional regulation
mitochondrial retrograde signaling
mitochondrial protein import
Application summary
Professor Hood¿s research program is aimed at investigating the role of exercise in enhancing the synthesis of mitochondria, the cellular organelles responsible for energy production, with a focus on skeletal muscle. Combining an analysis of mitochondrial biology with exercise physiology, Hood¿s studies allow us to understand the role of regular exercise in reversing mitochondrial dysfunction and cell death which occur during the normal process of aging, as well as in metabolic disorders such as diabetes and obesity. This research will have important implications for our understanding of the value of exercise in improving metabolic health, and in rejuvenating aging muscle.
