Grant: Discovery Grants Program - Individual
University of Western Ontario
$74,000.00
The Development of Enabling Syntheic Methodologies and Application to the Synthesis of Natural Products
FY 2020-21
Summary
This proposal describes the ongoing progress and new directions of our program which is aimed at developing new synthetic organic reactions and their application to the synthesis of important target molecules, usually of biological or medical importance. Such reactions center around several themes: 1. The use of donor-acceptor cyclopropanes for the synthesis of carbocycles and heterocycles, 2. The radical and carbenoid functionalization of heterocyclic motifs, 3. The development of new dipolar cycloaddiitons, and 4. The elaboration of the products from these processes into molecular frameworks of interest to the organic chemical community.
The target molecules selected for synthesis are often chosen as a showcase for the reactions we develop, however in some cases they are chosen for their sheer complexity and unusual structures. The benefits of our research program to the chemical community are twofold: 1. The methods we develop will be welcome additions to the chemical arsenal of the synthetic chemist and 2. The projects of target oriented synthesis provide the best training milieu known for synthetic chemists moving forward to subsequent endeavors, industrial or academic.
Program
Discovery Grants Program - Individual
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
RGPIN-2017-04760
Name nom
Kerr, Michael
Department département
Chemistry
Organization id
36
Institution établissement
University of Western Ontario
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2020
Competition year année de concours
2017
Award amount
74000
Program id
RGPIN
Program name en
Discovery Grants Program - Individual
Program name fr
Programme de subventions à la découverte - individuelles
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1504
Committee name en
Chemistry
Committee name fr
Chimie
Area of application code
504
Area of application group en
Manufacturing processes and products
Area of application group fr
Procédés et produits industriels
Area of application en
Human pharmaceuticals
Area of application fr
Produits pharmaceutiques administrables à l'homme
Research subject code
3703
Research subject group en
Organic chemistry
Research subject group fr
Chimie organique
Research subject en
Organic syntheses
Research subject fr
Synthèses organiques
Installment
inst:4-5
Partie
2
Nb partie
5
Application title
The Development of Enabling Syntheic Methodologies and Application to the Synthesis of Natural Products
Keyword
NSERC
Application summary
This proposal describes the ongoing progress and new directions of our program which is aimed at developing new synthetic organic reactions and their application to the synthesis of important target molecules, usually of biological or medical importance. Such reactions center around several themes: 1. The use of donor-acceptor cyclopropanes for the synthesis of carbocycles and heterocycles, 2. The radical and carbenoid functionalization of heterocyclic motifs, 3. The development of new dipolar cycloaddiitons, and 4. The elaboration of the products from these processes into molecular frameworks of interest to the organic chemical community.
The target molecules selected for synthesis are often chosen as a showcase for the reactions we develop, however in some cases they are chosen for their sheer complexity and unusual structures. The benefits of our research program to the chemical community are twofold: 1. The methods we develop will be welcome additions to the chemical arsenal of the synthetic chemist and 2. The projects of target oriented synthesis provide the best training milieu known for synthetic chemists moving forward to subsequent endeavors, industrial or academic.
