Grant: Operating Grant - Innovative Ebola Research Grants

A variety of strategies have been proposed and tested to treat people that are infected with Ebola virus. One very promising strategy is to give people antibodies that will recognize and neutralize the virus as a method to halt or slow the infection, providing opportunity for the person's own immune system to bring the infection under control leading to recovery. A highly efficient method to make large quantities of antibodies for treatment is to vaccinate horses with an ebola virus vaccine and then collect and purify the antibodies for use as a treatment. This product can be produced very quickly upon demand and similar products against other diseases have a very significant value in treating those infections. In this proposal we will test the antibodies in animals that will allow us to confirm that the antibody product will be effective.