Grant: Project Grant
University of Toronto
$554,626.00
The neural bases of diet-induced deficits in the control of food-seeking actions
FY 2017-18
Summary
Attempts to lose weight typically fail over the long term despite strong motivation and determined efforts. We recently found that excess sugar and fat in the diet strengthen habitual control, weakening flexible decision-making based on the value of outcomes produced by behaviour. This Project examines neural and cognitive changes produced by diet that prevent sound eating choices and undermine enduring weight loss efforts. It points the way to new therapies to restore flexible decision-making, for improved management of diet and weight.
Department
Program
Project Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
382414
Name
Corbit Laura
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
Behavioural Sciences - A: Neurobiological Basis of Behavioural Processes
Projecttitle
The neural bases of diet-induced deficits in the control of food-seeking actions
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$554,626
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Diet; Dorsal Striatum; Glutamate; Goal-Directed Learning; Habit Learning; Instrumental Learning
Abstract
Attempts to lose weight typically fail over the long term despite strong motivation and determined efforts. We recently found that excess sugar and fat in the diet strengthen habitual control, weakening flexible decision-making based on the value of outcomes produced by behaviour. This Project examines neural and cognitive changes produced by diet that prevent sound eating choices and undermine enduring weight loss efforts. It points the way to new therapies to restore flexible decision-making, for improved management of diet and weight.
Competitiondate
201803
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Corbit, Laura
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $554,626~ $0~
