Grant: Operating Grant
McMaster University
$896,081.00
Mechanisms and Reversing of Antibiotic Resistance
FY 2013-14
Summary
Antibiotics are the cornerstone of modern medicine. They not only control diseases caused by bacteria such as pneumonia but also enable a wide variety of medical procedures from surgery to cancer chemotherapy. Without antibiotics, medicine would return to 19th Century practices. We are in fact at risk of this occurring due to the fact that bacteria are becoming more resistant to our current drugs and few new ones are being discovered. My lab has been working on this problem for over 20 years and we have discovered some of the fundamental origins of resistance and how to address the problem. Over the next five years we will explore the molecular basis for antibiotic resistance and use this information in the development of new strategies to overcome it.
Department
Program
Operating Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
303919
Name
Wright Gerard D
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Microbiology & Infectious Diseases
Projecttitle
Mechanisms and Reversing of Antibiotic Resistance
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$896,081
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Antibiotic; Drugs; Enzymology; Genomics; High Throughput Screening; Natural Products
Abstract
Antibiotics are the cornerstone of modern medicine. They not only control diseases caused by bacteria such as pneumonia but also enable a wide variety of medical procedures from surgery to cancer chemotherapy. Without antibiotics, medicine would return to 19th Century practices. We are in fact at risk of this occurring due to the fact that bacteria are becoming more resistant to our current drugs and few new ones are being discovered. My lab has been working on this problem for over 20 years and we have discovered some of the fundamental origins of resistance and how to address the problem. Over the next five years we will explore the molecular basis for antibiotic resistance and use this information in the development of new strategies to overcome it.
Competitiondate
201403
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Wright, Gerard D
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $896,081~ $0~
