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Grant: Project Grant

Ottawa Hospital Research Institute

$256,274.00

Re(de)fining CKD to reduce cardiovascular disease in young adults

FY 2024-25

Summary
In the past half-century, great progress has been made in reducing heart disease among Canadians. However, there is a concerning trend: heart disease is increasing in young adults. Our previous research using data from Ontario, Canada found that young people with lower kidney function (about 20% below expected) were more likely to have serious heart problems. To further understand and improve the prevention of heart disease in young adults, we are focusing on three main questions: First, are young adults with lower kidney function more likely to develop high blood pressure, a major risk factor for heart disease? Second, how much does lower kidney function contribute to heart disease in young adults? Third, does kidney function help predict heart disease in young adults? By unraveling the complex relationship between kidney function and heart health in young adults, our work has the potential to change the way we approach heart disease. We strive to improve detection, and prevention of heart disease in young people with lower kidney function. This could lead to more targeted and effective treatments, ultimately reshaping how we fight heart disease.
Program
Project Grant
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
510133
Name
Sood Manish M
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Health systems / services
Prcname2
Clinical Investigation - D: Cardiovascular Systems
Projecttitle
Re(de)fining CKD to reduce cardiovascular disease in young adults
Programtype2
Operating Grants
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$256,274
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Cardiovascular Disease; Chronic Kidney Disease; Population Health; Risk Prediction; Young Adult
Abstract
In the past half-century, great progress has been made in reducing heart disease among Canadians. However, there is a concerning trend: heart disease is increasing in young adults. Our previous research using data from Ontario, Canada found that young people with lower kidney function (about 20% below expected) were more likely to have serious heart problems. To further understand and improve the prevention of heart disease in young adults, we are focusing on three main questions: First, are young adults with lower kidney function more likely to develop high blood pressure, a major risk factor for heart disease? Second, how much does lower kidney function contribute to heart disease in young adults? Third, does kidney function help predict heart disease in young adults? By unraveling the complex relationship between kidney function and heart health in young adults, our work has the potential to change the way we approach heart disease. We strive to improve detection, and prevention of heart disease in young people with lower kidney function. This could lead to more targeted and effective treatments, ultimately reshaping how we fight heart disease.
Competitiondate
202409
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Sood, Manish M
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $256,274~ $0~
Ottawa Hospital Research Institute - $256,274 Grant (… | Canada Spends