Grant: Engage Grants for Universities
Leonenko, Zoya (University of Waterloo)
$25,000.00
Characterization of Antigen-Adjuvant interactions by Atomic Force Microscopy
FY 2017-18 · 2017-04-25
Summary
Sanofi Pasteur is developing novel vaccine products, which contain antigens adsorbed to different types of_x000D_
adjuvants. Characterization and comprehensive analysis of the antigen-adjuvant interactions is of great_x000D_
importance for this development. Traditional ways of characterization, however do not allow measurement of_x000D_
molecular forces acting between reagents on molecular level which is of key importance._x000D_
The proposed new collaboration between Sanofi Pasteur and Dr.Zoya Leonenko's laboratory at the University_x000D_
of Waterloo has a goal to characterize adjuvant-antigen interactions by advanced biophysical methods, such as_x000D_
Atomic force microscopy, atomic force spectroscopy, and surface plasmon resonance, which would enhance_x000D_
the knowledge of the forces involved in such interactions and would help in the understanding of the relevance_x000D_
of the strength of antigen adsorption to adjuvants in Sanofi Pasteur's vaccine products. This new knowledge_x000D_
will lead to new product development and will help to accelerate pharmaceutical research by providing an_x000D_
advanced vaccine thus will contribute to the improvement of health of Canadian and worldwide community.
Program
Engage Grants for Universities
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
Proactive Disclosure - Grants and Contributions
As published
Additional Information
Grant or Award spanning more than one fiscal year. (2017-2018 to 2018-2019)
Additional Information (French)
Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2018-2019)
Agreement Number
EGP
Agreement Start Date
2017-04-25
Agreement Title
Characterization of Antigen-Adjuvant interactions by Atomic Force Microscopy
Agreement Title (French)
Characterization of Antigen-Adjuvant interactions by Atomic Force Microscopy
Agreement Type
Grant
Agreement Value
$25,000.00
Amendment Number
0
Organization Code
nserc-crsng
Organization
Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada
Program Name
Engage Grants for Universities
Program Name (French)
Subventions d'engagement partenarial pour les universités
Program Purpose
Sanofi Pasteur is developing novel vaccine products, which contain antigens adsorbed to different types of_x000D_
adjuvants. Characterization and comprehensive analysis of the antigen-adjuvant interactions is of great_x000D_
importance for this development. Traditional ways of characterization, however do not allow measurement of_x000D_
molecular forces acting between reagents on molecular level which is of key importance._x000D_
The proposed new collaboration between Sanofi Pasteur and Dr.Zoya Leonenko's laboratory at the University_x000D_
of Waterloo has a goal to characterize adjuvant-antigen interactions by advanced biophysical methods, such as_x000D_
Atomic force microscopy, atomic force spectroscopy, and surface plasmon resonance, which would enhance_x000D_
the knowledge of the forces involved in such interactions and would help in the understanding of the relevance_x000D_
of the strength of antigen adsorption to adjuvants in Sanofi Pasteur's vaccine products. This new knowledge_x000D_
will lead to new product development and will help to accelerate pharmaceutical research by providing an_x000D_
advanced vaccine thus will contribute to the improvement of health of Canadian and worldwide community.
Program Purpose (French)
Sanofi Pasteur is developing novel vaccine products, which contain antigens adsorbed to different types of_x000D_
adjuvants. Characterization and comprehensive analysis of the antigen-adjuvant interactions is of great_x000D_
importance for this development. Traditional ways of characterization, however do not allow measurement of_x000D_
molecular forces acting between reagents on molecular level which is of key importance._x000D_
The proposed new collaboration between Sanofi Pasteur and Dr.Zoya Leonenko's laboratory at the University_x000D_
of Waterloo has a goal to characterize adjuvant-antigen interactions by advanced biophysical methods, such as_x000D_
Atomic force microscopy, atomic force spectroscopy, and surface plasmon resonance, which would enhance_x000D_
the knowledge of the forces involved in such interactions and would help in the understanding of the relevance_x000D_
of the strength of antigen adsorption to adjuvants in Sanofi Pasteur's vaccine products. This new knowledge_x000D_
will lead to new product development and will help to accelerate pharmaceutical research by providing an_x000D_
advanced vaccine thus will contribute to the improvement of health of Canadian and worldwide community.
Recipient City
Ontario
Recipient Country
CA
Recipient Legal Name
Leonenko, Zoya (University of Waterloo)
Reference Number
GC-2017-Q1-00465
