Grant: Operating Grant
University of British Columbia
$278,880.00
Brain Imaging Studies of Oxidative Stress Cascade in Bipolar Disorder
FY 2009-10
Summary
Bipolar Disorder is a serious mood disorder that affects up to 2.4% of the population in Canada. The neurochemical changes in the brain that underlies expression of mood symptoms in this condition is unknown. Increased free radicals in the brain may cause damage to the brain and it is one of the hypothesis suggested to explain symptoms in this condition. However, this hypothesis needs to be tested directly by studying oxidative stress markers in bipolar patients and this study will use novel brain imaging techniques to study brain iron and one of the antioxidants glutathione.
Department
Program
Operating Grant
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
189906
Name
Yatham Lakshmi N
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Clinical
Prcname2
Behavioural Sciences - B: Clinical Behavioural Sciences
Projecttitle
Brain Imaging Studies of Oxidative Stress Cascade in Bipolar Disorder
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$278,880
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Bipolar Disorder; Brain Iron; Glutathione; Magentic Resonance Imaging; Oxidative Stress
Abstract
Bipolar Disorder is a serious mood disorder that affects up to 2.4% of the population in Canada. The neurochemical changes in the brain that underlies expression of mood symptoms in this condition is unknown. Increased free radicals in the brain may cause damage to the brain and it is one of the hypothesis suggested to explain symptoms in this condition. However, this hypothesis needs to be tested directly by studying oxidative stress markers in bipolar patients and this study will use novel brain imaging techniques to study brain iron and one of the antioxidants glutathione.
Competitiondate
200909
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Yatham, Lakshmi N
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $278,880~ $0~
