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Grant: Undergraduate: Mobility, musculoskeletal health and arthritis - ICS

University of British Columbia

$4,950.00

Assessing the role of tissue-resident mesenchymal progenitors in age-dependent skeletal muscle degeneration and fibrosis

FY 2011-12

Summary
It is well known that aging leads to decreases in both muscle size and function, which leads to a loss of mobility in the elderly. Unfortunately, a lack of understanding as to why this age-related degeneration occurs has prevented the development of therapies to treat it. A number of recent discoveries have identified a population of stem cells in muscle implicated in the process regeneration after tissue damage. The effect of aging on this stem cell population has yet to be investigated and could provide valuable insight into age-dependent muscle degeneration.
Program
Undergraduate: Mobility, musculoskeletal health and arthritis - ICS
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
251803
Name
Fernandes Justin
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Aging
Theme2
Biomedical
Prcname2
Undergraduate: Mobility, musculoskeletal health & arthritis - IMHA
Projecttitle
Assessing the role of tissue-resident mesenchymal progenitors in age-dependent skeletal muscle degeneration and fibrosis
Programtype2
Studentship Programs
Orgnameinp2
University of British Columbia
Cihramount2
$4,950
Cihrequipment2
$0
Programname2
Undergraduate: Mobility, musculoskeletal health and arthritis - ICS
Keyworddelim
Aging; Degeneration; Fibrosis; Fluorescence Activated Cell Sorting; Skeletal Muscle; Stem Cell
Abstract
It is well known that aging leads to decreases in both muscle size and function, which leads to a loss of mobility in the elderly. Unfortunately, a lack of understanding as to why this age-related degeneration occurs has prevented the development of therapies to treat it. A number of recent discoveries have identified a population of stem cells in muscle implicated in the process regeneration after tissue damage. The effect of aging on this stem cell population has yet to be investigated and could provide valuable insight into age-dependent muscle degeneration.
Competitiondate
201201
Approvedterm2
0 yr 3 mths
Pinamesdelim
Fernandes, Justin
Approvedterm
0 an 3 mois
Cihrcontribution2
Institute of Aging~ $4,950~ $0~