Grant: DSEN team grants: MAGIC and CAN-AIM

The CAnadian Network for Advanced Interdisciplinary Methods for comparative effectiveness research' (CAN-AIM) team is a pan-Canadian, highly interdisciplinary network of researchers working together to provide real-world information about drug safety and effectiveness for policymakers. Since the beginning, we have improved the validity and accuracy of Canadian research on the safety or benefits of particular drugs. Our aim is to continue to build on our team's expertise, develop methods to respond even more timely to future stakeholder queries and utilise novel sources of data to respond to queries. To achieve this, we are focusing on five main goals: -Improving data access and data enrichment with existing cohorts and supporting linkage of this data with administrative databases to optimize drug safety and effectiveness analyses; -Increasing collaboration between DSEN teams; -Creating tools to anticipate drug safety and effectiveness queries; -Improving analytical methods, including the use of new analytical methods to study gender/sex interactions in comparative effectiveness analysis; -Expanding ongoing research programs. We aim to make our research even more relevant for regulators through webinar series and seminars on relevant topics. We will also communicate with knowledge users to best understand stakeholder needs. Decision-makers need timely and relevant information to make informed-decisions on the safety or benefits of particular drugs. The next three years of activity will see CAN-AIM redouble its efforts to ensure that we are truly an indispensable agent of change for Canadian decision makers.