Grant: Project Grant

Endoscopic mucosal resection with margin ablation is a commonly used procedure to treat early-stage colorectal tumours. The technique used to perform margin ablation involves cauterizing the site of the tumour after it has been resected. Two new techniques have shown to reduce recurrence of colorectal tumours: snare tip soft coagulation (a metallic snare) and hybrid argon plasma coagulation (an argon probe that can apply current to tissues). In this proposed study, these two techniques will be compared against each other in a randomized controlled trial to establish which technique leads to the lowest percentage of recurrence at the next colonoscopy in patients. We expect that hybrid argon plasma coagulation will lead to much lower recurrence and lead to improved outcomes for patients, reduce the number of necessary exams, and reduce the total costs associated with treating early-stage colorectal tumours.