Grant: CIHR-ICRH Travel Awards - General pool
University of Toronto
$1,500.00
Establishing a gastruloid-based 3D model of human heart development to provide novel insights into congenital heart defects.
FY 2022-23
Summary
My thesis project aims to use gastruloids, an human pluripotent stem cell model that recapitulates aspects of gastrulation and early organogenesis, to model human heart development and gain novel insights into the pathophysiology of congenital heart defects. The ICRH promotes research into the causes and mechanisms of conditions associated with the heart. This project aims to find disease mechanisms and etiologies of congenital heart defects, the most common birth defect that affect 1 in 100 births, by recapitulating human heart development in vitro.
Department
Program
CIHR-ICRH Travel Awards - General pool
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
480721
Name
Chang Matthew Lok-Man
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases
Projecttitle
Establishing a gastruloid-based 3D model of human heart development to provide novel insights into congenital heart defects.
Programtype2
Undefined
Orgnameinp2
University of Toronto
Cihramount2
$1,500
Cihrequipment2
$0
Programname2
CIHR-ICRH Travel Awards - General pool
Keyworddelim
Congenital Heart Defects; Human Heart Model
Abstract
My thesis project aims to use gastruloids, an human pluripotent stem cell model that recapitulates aspects of gastrulation and early organogenesis, to model human heart development and gain novel insights into the pathophysiology of congenital heart defects. The ICRH promotes research into the causes and mechanisms of conditions associated with the heart. This project aims to find disease mechanisms and etiologies of congenital heart defects, the most common birth defect that affect 1 in 100 births, by recapitulating human heart development in vitro.
Competitiondate
202301
Approvedterm2
1 yr 0 mth
Pinamesdelim
Chang, Matthew Lok-Man
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $1,500~ $0~
