Grant: Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Concordia University
$95,150.00
The Development of a Functional, CGT-Relevant Cas12a crRNA Arrayed Knockout Library
FY 2024-25 · 2024-11-01
Summary
This proposal seeks to design and to construct a functional, CGT-relevant Cas12a crRNA arrayed library containing ~ 10,000 sequenced crRNA, which will then be available to the greater Canadian Cell and Gene Therapy community. To do so, we will leverage the expertise developed over the last few years in optimizing the design of Cas12a crRNA and the production of two PoC 96-well plate to ensure the feasibility in producing a larger-size library.
Department
Program
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Recipient
Location
Montreal|Montréal, Quebec, Canada
Recipient Type
Academia
Business Number
106966591
Type
Grant
Source
Proactive Disclosure - Grants and Contributions
Amendments
Each version of the agreement as published, oldest first, with its total as of that version. The amount above is the latest.
| Amendment | Date | Fiscal Year | Total |
|---|---|---|---|
| 0 | 2024-11-01 | 2024-25 | $95,150.00 |
| 1 | 2024-11-01 | 2024-25 | $95,150.00 |
As published
Additional Information
This agreement has been amended 1 time(s). The end date of this agreement has been modified by 243 days.
Additional Information (French)
Cet accord a été modifié 1 fois. La date de fin du présent accord a été changé de 243 jours.
Agreement End Date
2026-03-31
Agreement Number
1025925
Agreement Start Date
2024-11-01
Agreement Title
The Development of a Functional, CGT-Relevant Cas12a crRNA Arrayed Knockout Library
Agreement Title (French)
Création d’une banque fonctionnelle de clones de gènes inactivés disposés en grille pertinente pour les nucléotides CGT de l’ARNcr Cas12a
Agreement Type
Grant
Agreement Value
$95,150.00
Amendment Date
2025-09-26
Amendment Number
1
Description
This proposal seeks to design and to construct a functional, CGT-relevant Cas12a crRNA arrayed library containing ~ 10,000 sequenced crRNA, which will then be available to the greater Canadian Cell and Gene Therapy community. To do so, we will leverage the expertise developed over the last few years in optimizing the design of Cas12a crRNA and the production of two PoC 96-well plate to ensure the feasibility in producing a larger-size library.
Description (French)
Une banque d’ARNcr Cas12a fonctionnelle et pertinente pour les CGT, contenant environ 10 000 ARNcr séquencés, sera conçue, construite et ensuite mise à la disposition de l’ensemble de la communauté canadienne de thérapie cellulaire et génique. Pour ce faire, nous nous appuierons sur l’expertise développée au cours des dernières années dans l’optimisation de la conception de Cas12a ARNcr et la production de deux plaques à 96 puits au point d’intervention pour assurer la faisabilité de la production d’une bibliothèque de plus grande taille.
Expected Results
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.
Expected Results (French)
À court terme, les résultats prévus seront des collaborations renforcées entre l'industrie, le milieu universitaire et le gouvernement pour soutenir l'excellence en recherche. À moyen terme, les résultats attendus seront le développement de nouvelles technologies potentiellement perturbatrices avec des collaborateurs. À long terme, trouver des solutions collaboratives aux défis des politiques publiques et créer des systèmes d'innovation plus solides.
Federal Riding
Ville-Marie--Le Sud-Ouest--Île-des-Soeurs
Federal Riding (French)
Ville-Marie--Le Sud-Ouest--Île-des-Soeurs
Federal Riding Number
24077
NAICS Code
541710
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Program Name (French)
Programme de collaboration en science, en technologie et en innovation - Initiatives de collaboration en R-D
Program Purpose
Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.
Program Purpose (French)
Collaborer à des programmes multipartites de recherche-développement dans le but de profiter de la synergie entre la recherche transformatrice à haut risque et à haut rendement et le potentiel de découvertes scientifiques et de percées technologiques révolutionnaires dans des secteurs d’intervention prioritaires.
Recipient Business Number
106966591
Recipient City
Montreal|Montréal
Recipient Country
CA
Recipient Legal Name
Concordia University
Recipient Postal Code
H3G 1M8
Recipient Province or Territory
QC
Recipient Type
S
Reference Number
172-2024-2025-Q4-1025925