Contribution: Industrial Research Assistance Program – Contributions to Firms
ProteinQure Inc.
$728,000.00
UKRI Biomanufacturing - 10101341 Platforms for GPCRs - Novel technology platforms for computational design and cell-based screening of peptide libraries targeting orphan GPCRs
FY 2023-24 · 2024-03-01
Summary
As part of the international consortium project “Platforms for GPCRs - Novel technology platforms for computational design and cell-based screening of peptide libraries targeting orphan GPCRs”, this project will focus on ProteinQure and Orbit Discovery developing a new discovery platform for peptide therapeutics to drug previously undruggable, orphan G-Protein Coupled Receptors (GPCRs). The result will be new capabilities and products for ProteinQure to market. ProteinQure's Artificial Intelligence platform will design custom libraries containing over 500K peptides, and these peptides will be screened using Orbit Discovery’s platform. We will demonstrate the ability to drug orphan GPCRs, one of the hardest classes of disease targets.
Department
Program
Industrial Research Assistance Program – Contributions to FirmsIndustrial Research Assistance Program-Contributions to Firms (linked with high confidence)
Recipient
Location
Toronto|Toronto, Ontario, Canada
Recipient Type
For-profit organization
Business Number
788609683
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
Amendments
Each version of the agreement as published, oldest first, with its total as of that version. The amount above is the latest.
| Amendment | Date | Fiscal Year | Total |
|---|---|---|---|
| 0 | 2024-03-01 | 2023-24 | $678,000.00 |
| 1 | 2024-03-01 | 2023-24 | $728,000.00 |
As published
Additional Information
This agreement has been amended 1 time(s). The total amended value is 50,000 dollars.
Additional Information (French)
Cet accord a été modifié 1 fois La valeur totale des modifications est de 50 000 dollars.
Agreement End Date
2026-03-01
Agreement Number
1016558
Agreement Start Date
2024-03-01
Agreement Title
UKRI Biomanufacturing - 10101341 Platforms for GPCRs - Novel technology platforms for computational design and cell-based screening of peptide libraries targeting orphan GPCRs
Agreement Title (French)
UKRI Biofabrication - 10101341 Platforms for GPCRs - Nouvelles plateformes technologiques pour la conception computationnelle et le criblage cellulaire de bibliothèques de peptides ciblant les GPCRs orphelins.
Agreement Type
Contribution
Agreement Value
$728,000.00
Amendment Date
2025-02-13
Amendment Number
1
Coverage
IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation. | Les projets des Contributions aux entreprises stimulent la création de richesse au Canada grâce à l’innovation technologique.
Description
As part of the international consortium project “Platforms for GPCRs - Novel technology platforms for computational design and cell-based screening of peptide libraries targeting orphan GPCRs”, this project will focus on ProteinQure and Orbit Discovery developing a new discovery platform for peptide therapeutics to drug previously undruggable, orphan G-Protein Coupled Receptors (GPCRs). The result will be new capabilities and products for ProteinQure to market. ProteinQure's Artificial Intelligence platform will design custom libraries containing over 500K peptides, and these peptides will be screened using Orbit Discovery’s platform. We will demonstrate the ability to drug orphan GPCRs, one of the hardest classes of disease targets.
Description (French)
Dans le cadre du projet de consortium international «Platforms for GPCRs—Novel technology platforms for computational design and cell-based screening of peptide libraries targeting orphan GPCRs», ce projet se concentrera sur le développement par ProteinQure et Orbit Discovery d’une nouvelle plateforme de découverte de thérapies peptidiques pour le traitement de récepteurs orphelins couplés aux protéines G jusqu’à présent impossibles à traiter. Il en résultera de nouvelles capacités et de nouveaux produits à commercialiser pour ProteinQure. La plateforme d’intelligence artificielle de ProteinQure concevra des bibliothèques personnalisées contenant plus de 500 000 peptides, et ces peptides seront criblés à l’aide de la plateforme d’Orbit Discovery. Nous démontrerons notre capacité à traiter les RCPG orphelins, l’une des catégories de cibles pathologiques les plus difficiles à atteindre.
Expected Results
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Expected Results (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Federal Riding
Spadina--Fort York
Federal Riding (French)
Spadina--Fort York
Federal Riding Number
35101
NAICS Code
325410
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program – Contributions to Firms
Program Name (French)
Programme d’aide à la recherche industrielle – Contributions aux entreprises
Program Purpose
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Program Purpose (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Recipient Business Number
788609683
Recipient City
Toronto|Toronto
Recipient Country
CA
Recipient Legal Name
ProteinQure Inc.
Recipient Postal Code
M5V 2L1
Recipient Province or Territory
ON
Recipient Type
F
Reference Number
172-2023-2024-Q4-1016558
