Grant: Proof of Principle Program - Phase I
University of British Columbia
$150,000.00
Validation of Tissue and Cytology Microarray Spotter (TCMS) for Simultaneous Multiple Biomarker Detection in Cells
FY 2008-09
Summary
The aim of this application is to validate, for clinical application in a diagnostic laboratory setting, an instrument called a Tissue and Cytology Microarray Spotter (TCMS) suitable for immunohistochemistry (IHC), fluorescence in-situ hybridization (FISH), or both, of tissue sections or cell suspensions in an array format. We will confirm and optimize its performance, establish costs per sample labeled, and determine reproducibility. The validation will be done with commonly used, high volume biomarker tests on breast cancer samples and prenatal samples.
Department
Program
Proof of Principle Program - Phase I
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
175513
Name
Banerjee Diponkar
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Proof of Principle
Projecttitle
Validation of Tissue and Cytology Microarray Spotter (TCMS) for Simultaneous Multiple Biomarker Detection in Cells
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$150,000
Cihrequipment2
$0
Programname2
Proof of Principle Program - Phase I
Keyworddelim
Biomarker; Breast Cancer; Cytology; Fluorescence In-Situ Hybridization; Immunohistochemistry; Microarray
Abstract
The aim of this application is to validate, for clinical application in a diagnostic laboratory setting, an instrument called a Tissue and Cytology Microarray Spotter (TCMS) suitable for immunohistochemistry (IHC), fluorescence in-situ hybridization (FISH), or both, of tissue sections or cell suspensions in an array format. We will confirm and optimize its performance, establish costs per sample labeled, and determine reproducibility. The validation will be done with commonly used, high volume biomarker tests on breast cancer samples and prenatal samples.
Competitiondate
200810
Approvedterm2
1 yr 0 mth
Pinamesdelim
Banerjee, Diponkar
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $150,000~ $0~
