Canada Spends Logo

Explore our Budget 2026 analysis

Grant: Project Grant

Sunnybrook Research Institute (Toronto, Ontario)

$462,824.00

Canadian TAVR Triage Tool (CAN3T) for Wait-list Management in Aortic Stenosis: a Stepped-Wedged Cluster Randomized Registry-Based Trial

FY 2024-25

Summary
Severe Aortic stenosis (AS) is caused by thickening of the leaftlets of the aortic valve, restricting blood flow. Without treatment it has a very poor outlook. Transcatheter aortic valve implantation (TAVI/TAVR) is a novel minimally invasive therapy to treat AS. However, there are long wait-times for TAVI with poor outcomes while waiting. The Canadian TAVR Triage Tool (CAN3T) was developed to aid with wait-time management through a more evidence based triage of patients. In this trial, we are conducting a randomized control trial comparing status quo wait-time management, with that incorporating the CAN3T into the TAVI clinic work-flow. The trial is novel as it uses data collected routinely in Ontario as part of the CorHealth registry.
Program
Project Grant
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
507571
Name
Wijeysundera Harindra C
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Clinical
Prcname2
Clinical Investigation - D: Cardiovascular Systems
Projecttitle
Canadian TAVR Triage Tool (CAN3T) for Wait-list Management in Aortic Stenosis: a Stepped-Wedged Cluster Randomized Registry-Based Trial
Programtype2
Operating Grants
Orgnameinp2
Sunnybrook Research Institute (Toronto, Ontario)
Cihramount2
$462,824
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Aortic Stenosis; Cluster Randomized Trial; Wait Time Management
Abstract
Severe Aortic stenosis (AS) is caused by thickening of the leaftlets of the aortic valve, restricting blood flow. Without treatment it has a very poor outlook. Transcatheter aortic valve implantation (TAVI/TAVR) is a novel minimally invasive therapy to treat AS. However, there are long wait-times for TAVI with poor outcomes while waiting. The Canadian TAVR Triage Tool (CAN3T) was developed to aid with wait-time management through a more evidence based triage of patients. In this trial, we are conducting a randomized control trial comparing status quo wait-time management, with that incorporating the CAN3T into the TAVI clinic work-flow. The trial is novel as it uses data collected routinely in Ontario as part of the CorHealth registry.
Competitiondate
202409
Approvedterm2
4 yrs 0 mth
Pinamesdelim
Wijeysundera, Harindra C
Approvedterm
4 ans 0 mois
Cihrcontribution2
~ $462,824~ $0~