Grant: Research Tools and Instruments - Category 1 (<$150,000)
Queen's University
$71,525.00
Peptide Synthesizer For Biomaterial Preparation
FY 2014-15
Summary
Canadian citizens aged over 65 years currently consume over 40% of the annual healthcare budget. Within the next 20 years, this segment of the population is expected to increase from 12% to 21%, with a comparable increase in healthcare expenditures. Consequently, dramatic increases in healthcare costs are also expected over the next two decades. The financial burden of cardiovascular and orthopaedic care for the aging population has been called one of the greatest Canadian healthcare challenges of the 21st century. An emerging technology that has the potential to be a solution to this healthcare problem is tissue engineering. Tissue engineering involves the preparation of a biomaterial scaffold onto which the appropriate cells are seeded and grown either in vivo or in vitro to generate new tissue. With the demand for replacement tissues far exceeding the donor supply, tissue engineering to replace lost or damaged tissues is a promising concept that may revolutionize medicine. We are developing novel biomaterials and approaches for stem cell delivery to treat cardiovascular conditions, as well as to regenerate structural soft tissues such as ligaments and articular cartilage. The ability to synthesize the appropriate amounts of the peptides in a timely and cost-effective manner is key to the future development of these biomaterials and cell-based treatments. This application is to request funds to purchase a CEM Corp. Liberty Blue peptide synthesizer. This peptide synthesizer will be part of a shared laboratory for applied biomedical research housed in the Human Mobility Research Centre at Queen's University and will directly support our graduate program in Chemical Engineering. There is currently no peptide synthesizer present at Queen's University and its absence leads to significant delays in material development and thus research progress. The requested equipment will be used by 22 graduate and undergraduate students, and contribute to the research of 2 faculty members here at Queen's University.
Program
Research Tools and Instruments - Category 1 (<$150,000)
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
458687-2014
Name nom
Amsden, Brian
Department département
Chemical Engineering
Organization id
29
Institution établissement
Queen's University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2014
Competition year année de concours
2014
Award amount
71525
Program id
EQPEQ
Program name en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1511
Committee name en
Materials and Chemical Engineering
Committee name fr
Génie chimique et des matériaux
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
1902
Research subject group en
Biomedical engineering
Research subject group fr
Génie biomédical
Research subject en
Biomedical materials
Research subject fr
Matériaux biomédicaux
Partie
1
Nb partie
1
Application title
Peptide Synthesizer For Biomaterial Preparation
Keyword
NSERC
Application summary
Canadian citizens aged over 65 years currently consume over 40% of the annual healthcare budget. Within the next 20 years, this segment of the population is expected to increase from 12% to 21%, with a comparable increase in healthcare expenditures. Consequently, dramatic increases in healthcare costs are also expected over the next two decades. The financial burden of cardiovascular and orthopaedic care for the aging population has been called one of the greatest Canadian healthcare challenges of the 21st century. An emerging technology that has the potential to be a solution to this healthcare problem is tissue engineering. Tissue engineering involves the preparation of a biomaterial scaffold onto which the appropriate cells are seeded and grown either in vivo or in vitro to generate new tissue. With the demand for replacement tissues far exceeding the donor supply, tissue engineering to replace lost or damaged tissues is a promising concept that may revolutionize medicine. We are developing novel biomaterials and approaches for stem cell delivery to treat cardiovascular conditions, as well as to regenerate structural soft tissues such as ligaments and articular cartilage. The ability to synthesize the appropriate amounts of the peptides in a timely and cost-effective manner is key to the future development of these biomaterials and cell-based treatments. This application is to request funds to purchase a CEM Corp. Liberty Blue peptide synthesizer. This peptide synthesizer will be part of a shared laboratory for applied biomedical research housed in the Human Mobility Research Centre at Queen's University and will directly support our graduate program in Chemical Engineering. There is currently no peptide synthesizer present at Queen's University and its absence leads to significant delays in material development and thus research progress. The requested equipment will be used by 22 graduate and undergraduate students, and contribute to the research of 2 faculty members here at Queen's University.
