Grant: Project Grant
University of Toronto
$669,375.00
Targeting CARMIL1 in Treatment of Periodontitis
FY 2018-19
Summary
Gum tissue around the teeth provides an important protective and sealing function. This tissue prevents germs from getting into the deeper tissues that hold the tooth to the jaw bone. Currently we don't understand how gum health and function are preserved, particularly when there is inflammation in various types of gum diseases. The purpose of this study is to develop a new and promising approach for control of inflammation and bone loss and to thereby maintain the attachment of the gums to the teeth.
Department
Program
Project Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
388364
Name
McCulloch Christopher A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Musculoskeletal Health and Arthritis
Theme2
Biomedical
Prcname2
Clinical Investigation - B: Arthritis, Bone, Skin and Cartilage
Projecttitle
Targeting CARMIL1 in Treatment of Periodontitis
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$669,375
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Collagen; Collagenase; Fibroblasts; Gingiva; Il-1; Inflammation; Periodontal Diseases; Prevention
Abstract
Gum tissue around the teeth provides an important protective and sealing function. This tissue prevents germs from getting into the deeper tissues that hold the tooth to the jaw bone. Currently we don't understand how gum health and function are preserved, particularly when there is inflammation in various types of gum diseases. The purpose of this study is to develop a new and promising approach for control of inflammation and bone loss and to thereby maintain the attachment of the gums to the teeth.
Competitiondate
201809
Approvedterm2
5 yrs 0 mth
Pinamesdelim
McCulloch, Christopher A
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $669,375~ $0~
