Grant: Planning Grants: Priority Announcement - Reproductive and Child Health
Children's Hospital of Eastern Ontario Research Institute Inc
$17,700.00
Prognosticators of persistent concussion symptoms following pediatric minor traumatic head injury
FY 2011-12
Summary
Concussion is a silent epidemic and serious public health problem. Post-concussion, many children suffer recurrent headaches and other physical, pyschological and behavioral symptoms known as persistent concussion symptoms (PCS) leading to increased morbidity. The literature indicates 59% of children remain symptomatic at 1 month follow-up, 11% at 3 months and 2% beyond 1 year. Even mild repeated brain injuries during school-aged years have potential for permanent learning disabilities and neuropsychiatric problems. Studies link multiple head injuries to the development of traumatic encephalopathy similar to Alzheimer's.
To date, we are unable to identify which children will suffer PCS, as no accepted set of prognosticators exists. A recent Pediatrics article concluded: "Future efforts should focus on creating a rapid, easily administered tool for detecting...the likelihood for developing post-concussive syndrome."
A CIHR grant supporting a collaborative meeting (March 29-30, 2012) would expand on pilot data to build a prospective, multicentre study to predict the presence and duration of PCS in children using the Pediatric Emergency Research Canada (PERC) network. We anticipate bringing together national and international experts for study design: consensus on inclusion criteria, identification and definitition of study prognosticators, follow-up harmonization, determination of measurement tools, and confirmation of primary and secondary outcome measures. Deliverables inlcude: a collaborative research question with defined prognosticators and a team prepared to write, apply for, and conduct a multicentre trial.
We possess diverse expertise in pediatric concussion (Pediatric Emergency Medicine, Sports Medicine, Neuropsychology, Neurosurgery, and Neurology). Our meeting will draw upon our PERC leadership and supportive organizations (Ontario Neurotrauma Foundation, ThinkFirst) to create a multicentre study with the aim of minimizing PCS in children
Department
Program
Planning Grants: Priority Announcement - Reproductive and Child Health
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
246163
Name
Zemek Roger
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Human Development, Child and Youth Health
Theme2
Clinical
Prcname2
Planning Grants
Projecttitle
Prognosticators of persistent concussion symptoms following pediatric minor traumatic head injury
Programtype2
Miscellaneous Programs
Orgnameinp2
Children's Hospital of Eastern Ontario Research Institute Inc
Cihramount2
$17,700
Cihrequipment2
$0
Programname2
Planning Grants: Priority Announcement - Reproductive and Child Health
Keyworddelim
Capacity Building; Clinical Decision Rule; Concussion; Emergency; Knowledge Exchange; Multi-Centre Research Network; Multi-Disciplinary; Pediatrics; Traumatic Head Injury Sequalae
Abstract
Concussion is a silent epidemic and serious public health problem. Post-concussion, many children suffer recurrent headaches and other physical, pyschological and behavioral symptoms known as persistent concussion symptoms (PCS) leading to increased morbidity. The literature indicates 59% of children remain symptomatic at 1 month follow-up, 11% at 3 months and 2% beyond 1 year. Even mild repeated brain injuries during school-aged years have potential for permanent learning disabilities and neuropsychiatric problems. Studies link multiple head injuries to the development of traumatic encephalopathy similar to Alzheimer's.
To date, we are unable to identify which children will suffer PCS, as no accepted set of prognosticators exists. A recent Pediatrics article concluded: "Future efforts should focus on creating a rapid, easily administered tool for detecting...the likelihood for developing post-concussive syndrome."
A CIHR grant supporting a collaborative meeting (March 29-30, 2012) would expand on pilot data to build a prospective, multicentre study to predict the presence and duration of PCS in children using the Pediatric Emergency Research Canada (PERC) network. We anticipate bringing together national and international experts for study design: consensus on inclusion criteria, identification and definitition of study prognosticators, follow-up harmonization, determination of measurement tools, and confirmation of primary and secondary outcome measures. Deliverables inlcude: a collaborative research question with defined prognosticators and a team prepared to write, apply for, and conduct a multicentre trial.
We possess diverse expertise in pediatric concussion (Pediatric Emergency Medicine, Sports Medicine, Neuropsychology, Neurosurgery, and Neurology). Our meeting will draw upon our PERC leadership and supportive organizations (Ontario Neurotrauma Foundation, ThinkFirst) to create a multicentre study with the aim of minimizing PCS in children
Competitiondate
201110
Approvedterm2
1 yr 0 mth
Pinamesdelim
Zemek, Roger
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $17,700~ $0~
