Canada Spends Logo

Explore our Budget 2026 analysis

Grant: Master's Award: Canada Graduate Scholarships

Toronto Metropolitan University

$17,500.00

Effects of methylphenidate on attention and impulse control tasks in children with ADHD

FY 2022-23

Summary
Attention-Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental disorder characterized by persistent patterns of impaired attention and hyperactivity-impulsivity. Executive functioning is adversely affected in ADHD, especially in attentional and impulse control. Many children diagnosed with ADHD use the psychostimulant methylphenidate regularly to improve overall daily functioning, however, there is a lack of data on whether medications will improve performance in tasks of attentional and impulse control. The proposed study aims to measure attentional and impulse control in children diagnosed with ADHD before and after delivering methylphenidate. We hypothesize that the use of methylphenidate will improve the performance in the administered task. Eligible participants will be children diagnosed with ADHD with no history of psychostimulant use. Participants will complete a visual cue task prior to taking methylphenidate to measure baseline levels. In the task, they will be cued by an arrow to one of eight surrounding pools and asked to complete a button press response for a fish target or refrain from responding for a tadpole target. They will then be placed on a six-week drug trial and complete the same visual cue task at the same time of day in lab. A paired-samples t-test will be calculated to compare the mean correct responses in both pre- and post-drug administration conditions. We expect that the mean of correct responses will be significantly higher in the post-drug administration trial, demonstrating medication effectiveness in attentional and impulse control in children with ADHD. The results will be evidence for the use of methylphenidate to target attentional and impulse control deficits in ADHD to improve overall daily functioning.
Program
Master's Award: Canada Graduate Scholarships
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
486620
Name
Avitzur Carmel
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases - Awards Programs
Projecttitle
Effects of methylphenidate on attention and impulse control tasks in children with ADHD
Programtype2
Studentship Programs
Orgnameinp2
Toronto Metropolitan University
Cihramount2
$17,500
Cihrequipment2
$0
Programname2
Master's Award: Canada Graduate Scholarships
Keyworddelim
Attention-Deficit/Hyperactivity Disorder; Attentional Control; Executive Functioning; Methylphenidate; Psychostimulants; Response Inhibition; Visual Attention Task
Abstract
Attention-Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental disorder characterized by persistent patterns of impaired attention and hyperactivity-impulsivity. Executive functioning is adversely affected in ADHD, especially in attentional and impulse control. Many children diagnosed with ADHD use the psychostimulant methylphenidate regularly to improve overall daily functioning, however, there is a lack of data on whether medications will improve performance in tasks of attentional and impulse control. The proposed study aims to measure attentional and impulse control in children diagnosed with ADHD before and after delivering methylphenidate. We hypothesize that the use of methylphenidate will improve the performance in the administered task. Eligible participants will be children diagnosed with ADHD with no history of psychostimulant use. Participants will complete a visual cue task prior to taking methylphenidate to measure baseline levels. In the task, they will be cued by an arrow to one of eight surrounding pools and asked to complete a button press response for a fish target or refrain from responding for a tadpole target. They will then be placed on a six-week drug trial and complete the same visual cue task at the same time of day in lab. A paired-samples t-test will be calculated to compare the mean correct responses in both pre- and post-drug administration conditions. We expect that the mean of correct responses will be significantly higher in the post-drug administration trial, demonstrating medication effectiveness in attentional and impulse control in children with ADHD. The results will be evidence for the use of methylphenidate to target attentional and impulse control deficits in ADHD to improve overall daily functioning.
Competitiondate
202212
Approvedterm2
1 yr 0 mth
Pinamesdelim
Avitzur, Carmel
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $17,500~ $0~