Grant: Idea to Innovation
Brock University
$10,000.00
The development of dual property Gd (III) and Mn(II) MRI contrast agens with high relaxivities
FY 2013-14
Summary
The technology relates to the development of magnetic resonance imaging (MRI) contrast agents that have improved safety profiles and customizable ligands for enhanced therapeutic and diagnostic activity. Pilkington's lab has developed contrast agents that are superior to current market agents. - The contrast agents have higher relaxivities resulting in superior MRI image quality;- The agents are stable, thus reducing the chance of biotoxic side effects from the release of the metal centre; and- The Pilkington lab has implemented a method that allows for the attachment of diagnostically and therapeutically relevant ligands to a metal centre resulting in agents that can both localize to a desirable region and induce a potentially therapeutic effect.
Program
Idea to Innovation
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
461349-2014
Name nom
Pilkington, Melanie
Department département
Chemistry
Organization id
22
Institution établissement
Brock University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2013
Competition year année de concours
2014
Award amount
10000
Program id
I2IPJ
Program name en
Idea to Innovation
Program name fr
De l'idée à l'innovation
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
96
Committee name en
RPP Internal Decision Cttee
Committee name fr
Cté de décision interne - PPR
Area of application code
1211
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Medical and health sciences
Area of application fr
Sciences médicales et de la santé
Research subject code
3603
Research subject group en
Inorganic chemistry
Research subject group fr
Chimie inorganique
Research subject en
Bio-inorganic chemistry
Research subject fr
Chimie bio-inorganique
Partie
1
Nb partie
1
Application title
The development of dual property Gd (III) and Mn(II) MRI contrast agens with high relaxivities
Keyword
NSERC
Application summary
The technology relates to the development of magnetic resonance imaging (MRI) contrast agents that have improved safety profiles and customizable ligands for enhanced therapeutic and diagnostic activity. Pilkington's lab has developed contrast agents that are superior to current market agents. - The contrast agents have higher relaxivities resulting in superior MRI image quality;- The agents are stable, thus reducing the chance of biotoxic side effects from the release of the metal centre; and- The Pilkington lab has implemented a method that allows for the attachment of diagnostically and therapeutically relevant ligands to a metal centre resulting in agents that can both localize to a desirable region and induce a potentially therapeutic effect.
