Grant: Project Grant

Severe muscle loss in cancer patients has been associated with increased physical disability, extended hospitalization, infectious and noninfectious complications, increased risk of severe toxicity during cancer treatment, poor quality of life and shortened survival. Adequate protein and energy intake (calories) are key to sustain muscle mass and overall health. However, current nutritional recommendations are not specific or evidence-based. The aim of this project is to determine the energy and protein needs of patients with cancer. Protein requirements will be determined using a novel, non-invasive approach. We will assess energy needs using several methods including a free-living method and a self-contained unit (similar to a small hotel room) that precisely calculates the calories a person uses in a day. Our study has never been conducted in people with cancer. Our results will inform nutritional recommendations and guidelines with the ultimate goal of improving outcomes for people suffering from cancer.