Grant: Canada Research Chairs

Nonlinear microscopy is revolutionizing the imaging and characterization of biomaterials. The simultaneous integration of several imaging techniques is known as multimodal microscopy. We will continue the development of novel chemically-specific and label-free nonlinear optical imaging modalities that can be integrated into our custom-built ultrafast-laser-based nonlinear optical microscope, for true multimodal nonlinear-optical microscopy. Such modalities will include second-harmonic generation and two-photon fluorescence, as well as stimulated vibrational techniques such as CARS and SRS. This research will then enable rapid micro-spectroscopic characterization of structure and dynamic processes in natural and hybrid biomaterials of technological and biomedical importance to Canada.