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Grant: Foundation Grant

University of Toronto

$2,365,558.00

Development of non-invasive diagnostics for disease prevention and control

FY 2015-16

Summary
High-performance platforms that diagnose disease and predict the progression of disease are urgently needed for both clinical patient care and clinical research. The aim of my research group is to generate novel systems applicable to the detection and characterization of cancer, infectious disease and other disease states. In order to accomplish this goal, we have developed platforms that integrate molecular analysis into disease diagnostics with superior sensitivity and specificity to technology that is currently available. We are developing a toolbox of assays that report on specific disease markers and we will use these developed technologies to further understand the role cellular biomarkers play in disease progression. These assays will be translated for clinical use to enable precision medicine based on molecular-level information to become routine. This research has the potential to impact current detection and treatment considerations for cancer and infectious disease in health care settings.
Program
Foundation Grant
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
333713
Name
Kelley Shana O
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Foundation Grant
Projecttitle
Development of non-invasive diagnostics for disease prevention and control
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$2,365,558
Cihrequipment2
$0
Programname2
Foundation Grant
Keyworddelim
Antimicrobial Susceptibility; Bioanalytical; Biosensing; Cancer Biomarkers; Circulating Tumor Cells; Diagnostic; Infectious Disease; Nanotechnology
Abstract
High-performance platforms that diagnose disease and predict the progression of disease are urgently needed for both clinical patient care and clinical research. The aim of my research group is to generate novel systems applicable to the detection and characterization of cancer, infectious disease and other disease states. In order to accomplish this goal, we have developed platforms that integrate molecular analysis into disease diagnostics with superior sensitivity and specificity to technology that is currently available. We are developing a toolbox of assays that report on specific disease markers and we will use these developed technologies to further understand the role cellular biomarkers play in disease progression. These assays will be translated for clinical use to enable precision medicine based on molecular-level information to become routine. This research has the potential to impact current detection and treatment considerations for cancer and infectious disease in health care settings.
Competitiondate
201509
Approvedterm2
7 yrs 0 mth
Pinamesdelim
Kelley, Shana O
Approvedterm
7 ans 0 mois
Cihrcontribution2
~ $2,365,558~ $0~