Grant: Canada Research Chairs
York University
$120,000.00
Neurophysiology
FY 2021-22
Summary
The prevalence of Autism Spectrum Disorder (ASD), a complex condition characterized by impairments in cognition, communication and social skills, is escalating in Canada. ASDs often result from dysfunctional brain cell connections, known as synapses. Mutations in genes coding for synapse organizing proteins are considered a key pathology contributing to ASDs. To better understand synapse dysfunction in ASD, I study the effects of loss of the synaptic organizer MDGA2, which when reduced recapitulates phenotypes observed in some cases of ASD. My goal is to understand and hopefully reverse cellular mechanisms responsible for ASD resulting from loss of MDGA2.
Program
Canada Research Chairs
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
CRC-2017-00279
Name nom
Connor, Steven
Department département
Head Office
Organization id
38
Institution établissement
York University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2021
Competition year année de concours
2017
Award amount
120000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
5100
Research subject group en
Cell biology
Research subject group fr
Biologie cellulaire
Research subject en
Cell biology
Research subject fr
Biologie cellulaire
Installment
inst:4-1
Partie
1
Nb partie
4
Application title
Neurophysiology
Keyword
NSERC
Application summary
The prevalence of Autism Spectrum Disorder (ASD), a complex condition characterized by impairments in cognition, communication and social skills, is escalating in Canada. ASDs often result from dysfunctional brain cell connections, known as synapses. Mutations in genes coding for synapse organizing proteins are considered a key pathology contributing to ASDs. To better understand synapse dysfunction in ASD, I study the effects of loss of the synaptic organizer MDGA2, which when reduced recapitulates phenotypes observed in some cases of ASD. My goal is to understand and hopefully reverse cellular mechanisms responsible for ASD resulting from loss of MDGA2.
