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Grant: Project Grant

University of British Columbia

$898,876.00

Improved Assessment of Disease in Lymphoma Patients using Quantitative PET Imaging

FY 2019-20

Summary
In this work, we aim to improve quantitative accuracy of PET scans used for imaging of patients with lymphoma, a cancer that begins in cells of the lymph system. We aim to measure the volume of tumors in the patients, which is a measure that has potential for much improved assessment of disease, and we aim to achieve this in a fully automated way using artificial intelligence (AI) based methods, and to routinely report this measure to our clinicians in our systems in the clinic. In addition, we aim to extract and study different features from the images in order to demonstrate which features, or their combinations as obtained using AI-based methods, can better predict patient outcomes and enable potentially improved personalization of therapy for lymphoma patients. Our proposed study includes participation of multiple international collaborators with extensive data from lymphoma cancer patients for improved assessment of our developed techniques.
Program
Project Grant
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
421329
Name
Rahmim Arman
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Medical Physics & Imaging
Projecttitle
Improved Assessment of Disease in Lymphoma Patients using Quantitative PET Imaging
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$898,876
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Artificial Intelligence; Image Processing; Machine Learning; Molecular Imaging; Nuclear Medicine; Personalized Cancer Therapy; Pet/Ct; Quantitative Imaging; Radiomics
Abstract
In this work, we aim to improve quantitative accuracy of PET scans used for imaging of patients with lymphoma, a cancer that begins in cells of the lymph system. We aim to measure the volume of tumors in the patients, which is a measure that has potential for much improved assessment of disease, and we aim to achieve this in a fully automated way using artificial intelligence (AI) based methods, and to routinely report this measure to our clinicians in our systems in the clinic. In addition, we aim to extract and study different features from the images in order to demonstrate which features, or their combinations as obtained using AI-based methods, can better predict patient outcomes and enable potentially improved personalization of therapy for lymphoma patients. Our proposed study includes participation of multiple international collaborators with extensive data from lymphoma cancer patients for improved assessment of our developed techniques.
Competitiondate
202003
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Rahmim, Arman
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $898,876~ $0~