Grant: Operating Grant
Research Institute of the McGill University Health Centre
$387,135.00
Urinary Tract Defects:Identifying Causative Genes from Mouse Models
FY 2008-09
Summary
Our laboratory has discovered a mouse model that has a congenital urinary tract defect known as vesicoureteric reflux. In this grant, we will use this mouse model to understand the genetic basis of vesicoureteric reflux and to elucidate the mechanism by which the ureter fails to insert correctly into the bladder wall. In the final aim of this grant, we will determine whether the gene (s) that are mutated in this mouse model are associated with vesicoureteric reflux in humans.
Department
Program
Operating Grant
Location
Quebec, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
172393
Name
Gupta Indra R
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Human Development, Child and Youth Health
Theme2
Biomedical
Prcname2
Experimental Medicine
Projecttitle
Urinary Tract Defects:Identifying Causative Genes from Mouse Models
Programtype2
Operating Grants
Orgnameinp2
Research Institute of the McGill University Health Centre
Cihramount2
$387,135
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Kidney And Urinary Tract Development; Mouse Genetics; Vesicoureteric Reflux
Abstract
Our laboratory has discovered a mouse model that has a congenital urinary tract defect known as vesicoureteric reflux. In this grant, we will use this mouse model to understand the genetic basis of vesicoureteric reflux and to elucidate the mechanism by which the ureter fails to insert correctly into the bladder wall. In the final aim of this grant, we will determine whether the gene (s) that are mutated in this mouse model are associated with vesicoureteric reflux in humans.
Competitiondate
200809
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Gupta, Indra R
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $387,135~ $0~
