Grant: Canada Research Chairs
University of British Columbia
$120,000.00
Developmental Neurobiology
FY 2018-19
Summary
Movement precision is ultimately determined by the resolution of the motor circuit at the level of single neurons and synapses. However, other factors such as muscle quality/quantity and joint flexibility also affect locomotion. In addition, current synaptic labeling techniques in most organisms do not have enough resolution to distinguish synapses between neighboring neurons. Hence, it is not clear to what extent the fineness of the motor circuit determines physical ability. Using a genetic model organism Caenorhabditis elegans, which has a simple locomotion circuit, I will study molecular mechanisms of synapse patterning and how it affects locomotion.
Program
Canada Research Chairs
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
1000230476-2014
Name nom
Mizumoto, Kota
Department département
Department of Zoology
Organization id
2
Institution établissement
University of British Columbia
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2018
Competition year année de concours
2014
Award amount
120000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
5300
Research subject group en
Molecular biology
Research subject group fr
Biologie moléculaire
Research subject en
Molecular biology
Research subject fr
Biologie moléculaire
Partie
0
Nb partie
NA
Application title
Developmental Neurobiology
Keyword
NSERC
Application summary
Movement precision is ultimately determined by the resolution of the motor circuit at the level of single neurons and synapses. However, other factors such as muscle quality/quantity and joint flexibility also affect locomotion. In addition, current synaptic labeling techniques in most organisms do not have enough resolution to distinguish synapses between neighboring neurons. Hence, it is not clear to what extent the fineness of the motor circuit determines physical ability. Using a genetic model organism Caenorhabditis elegans, which has a simple locomotion circuit, I will study molecular mechanisms of synapse patterning and how it affects locomotion.
