Grant: CIHR New Investigator
University of British Columbia
$300,000.00
Optimizing exercise for improving cardiometabolic health and inflammation in individuals with prediabetes and type 2 diabetes
FY 2014-15
Summary
Exercise is regarded as cornerstone for the prevention and treatment of type 2 diabetes. However, the optimal exercise strategy for improving the cardiovascular and metabolic health of individuals with prediabetes and tyep 2 diabetes is not yet known. This research program seeks to help identify what type of exercise is most beneficial for improving cardiovascular fitness, blood glucose control, and markers of inflammation in individuals with, and at risk for, type 2 diabetes. A novel form of time-efficient exercise called high-intensity interval training ("HIIT") will be compared to traditional moderate-intensity continuous training and resistance training. It is hypothesized that HIIT will lead to health benefits that are equal, or superior, to traditional exercise but will do so in less time. In addition, this research will test whether the benefits of exercise can be improved by combining HIIT with nutritional interventions, and whether individuals can stick to HIIT on their own in order to gain continued benefits of this type of exercise.
Department
Program
CIHR New Investigator
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
319960
Name
Little Jonathan P
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Clinical
Prcname2
New Investigators C
Projecttitle
Optimizing exercise for improving cardiometabolic health and inflammation in individuals with prediabetes and type 2 diabetes
Programtype2
Salary Programs
Orgnameinp2
University of British Columbia
Cihramount2
$300,000
Cihrequipment2
$0
Programname2
CIHR New Investigator
Keyworddelim
Endothelial Function; Exercise; Glucose Control; Immunology; Inflammation; Insulin Sensitivity; Metabolism; Monocyte; Prediabetes; Type 2 Diabetes
Abstract
Exercise is regarded as cornerstone for the prevention and treatment of type 2 diabetes. However, the optimal exercise strategy for improving the cardiovascular and metabolic health of individuals with prediabetes and tyep 2 diabetes is not yet known. This research program seeks to help identify what type of exercise is most beneficial for improving cardiovascular fitness, blood glucose control, and markers of inflammation in individuals with, and at risk for, type 2 diabetes. A novel form of time-efficient exercise called high-intensity interval training ("HIIT") will be compared to traditional moderate-intensity continuous training and resistance training. It is hypothesized that HIIT will lead to health benefits that are equal, or superior, to traditional exercise but will do so in less time. In addition, this research will test whether the benefits of exercise can be improved by combining HIIT with nutritional interventions, and whether individuals can stick to HIIT on their own in order to gain continued benefits of this type of exercise.
Competitiondate
201412
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Little, Jonathan P
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $300,000~ $0~