Grant: Project Grant
University of Calgary
$986,205.00
Stress hyper-reactivity and GABA plasticity
FY 2015-16
Summary
In Canada, approximately 9% of the population will suffer from post-traumatic stress disorder (PTSD). PTSD patients relive traumatic events, exhibit hyper-vigilance, and exaggerated startle response. Stress is also a trigger for psychiatric disorders and over 90% of PTSD patients experience debilitating comorbidities such as major depression and generalized anxiety. The overall objective of the proposed work is to understand how the brain remembers stress, and then use this information to disrupt the "memories" of stressful events.
Department
Program
Project Grant
Recipient
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
345886
Name
Bains Jaideep S
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
Project Grant Competition
Projecttitle
Stress hyper-reactivity and GABA plasticity
Programtype2
Operating Grants
Orgnameinp2
University of Calgary
Cihramount2
$986,205
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Chloride; Electrophysiology; Gaba; Hypothalamus; Plasticity; Stress; Synapse
Abstract
In Canada, approximately 9% of the population will suffer from post-traumatic stress disorder (PTSD). PTSD patients relive traumatic events, exhibit hyper-vigilance, and exaggerated startle response. Stress is also a trigger for psychiatric disorders and over 90% of PTSD patients experience debilitating comorbidities such as major depression and generalized anxiety. The overall objective of the proposed work is to understand how the brain remembers stress, and then use this information to disrupt the "memories" of stressful events.
Competitiondate
201603
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Bains, Jaideep S
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $986,205~ $0~
