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Grant: Catalyst Grant: Digital Health

University of Alberta

$100,000.00

Foundational Research Toward Machine Learning-Based Decision Support for Safer Opioid Prescribing in Emergency Department Patients with Acute Fractures

FY 2025-26

Summary
When a patient arrives in the Emergency Department (ED) with an extremity fracture (e.g., arm, leg, wrist), doctors must treat the pain effectively. While simple pain relievers work for some, many fracture patients require opioid prescriptions upon discharge. However, the ongoing opioid crisis has led ED doctors to be more cautious, sometimes resulting in undertreated pain that delays recovery and mobility. The risk of an opioid prescription leading to Opioid Use Disorder (OUD) or long-term opioid use varies greatly depending on the individual patient and the prescription details. This creates a "prescriber's dilemma": how to provide adequate pain relief without putting the patient at unnecessary risk. This project has two parallel aims. First, we will use Machine Learning (ML) to build a risk prediction model using Alberta's electronic health records, combining patient history, demographics, and socio-economic factors to predict an individual's risk of OUD or prolonged opioid use after an ED fracture visit. We will rigorously test the model's fairness across groups defined by age, sex, gender, rurality, and socio-economic status to ensure it does not perpetuate health inequities. Second, we will conduct interviews with patients and ED physicians to understand how they think about opioid risk, what information they need for shared decision-making, and what barriers exist to having these conversations in a busy ED. Patient partners with lived experience will collaborate throughout-helping design the study, review the model for potential biases, co-conduct interviews, and shape how findings are shared. Together, these two streams will provide the foundation for a future clinical decision support tool embedded in the electronic medical record, helping doctors and patients make safer, more informed prescribing decisions at the bedside. The long-term impact will be more equitable, patient-centered pain management for fracture patients across urban and rural Alberta.
Program
Catalyst Grant: Digital Health
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
561141
Name
Hayward Jake
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Health Services and Policy Research
Theme2
Health systems / services
Prcname2
Catalyst Grant - Digital Health
Projecttitle
Foundational Research Toward Machine Learning-Based Decision Support for Safer Opioid Prescribing in Emergency Department Patients with Acute Fractures
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$100,000
Cihrequipment2
$0
Programname2
Catalyst Grant: Digital Health
Keyworddelim
Fracture Management; Opioid Prescribing; Opioid Use Disorder
Abstract
When a patient arrives in the Emergency Department (ED) with an extremity fracture (e.g., arm, leg, wrist), doctors must treat the pain effectively. While simple pain relievers work for some, many fracture patients require opioid prescriptions upon discharge. However, the ongoing opioid crisis has led ED doctors to be more cautious, sometimes resulting in undertreated pain that delays recovery and mobility. The risk of an opioid prescription leading to Opioid Use Disorder (OUD) or long-term opioid use varies greatly depending on the individual patient and the prescription details. This creates a "prescriber's dilemma": how to provide adequate pain relief without putting the patient at unnecessary risk. This project has two parallel aims. First, we will use Machine Learning (ML) to build a risk prediction model using Alberta's electronic health records, combining patient history, demographics, and socio-economic factors to predict an individual's risk of OUD or prolonged opioid use after an ED fracture visit. We will rigorously test the model's fairness across groups defined by age, sex, gender, rurality, and socio-economic status to ensure it does not perpetuate health inequities. Second, we will conduct interviews with patients and ED physicians to understand how they think about opioid risk, what information they need for shared decision-making, and what barriers exist to having these conversations in a busy ED. Patient partners with lived experience will collaborate throughout-helping design the study, review the model for potential biases, co-conduct interviews, and shape how findings are shared. Together, these two streams will provide the foundation for a future clinical decision support tool embedded in the electronic medical record, helping doctors and patients make safer, more informed prescribing decisions at the bedside. The long-term impact will be more equitable, patient-centered pain management for fracture patients across urban and rural Alberta.
Competitiondate
202603
Approvedterm2
1 yr 0 mth
Pinamesdelim
Hayward, Jake; Dowling, Shawn K; Cao, Bo; Li, Henry
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $100,000~ $0~