Grant: Randomized Controlled Trials
University of British Columbia
$999,997.00
Study to Assess Longer-term Opioid Medication Effectiveness (SALOME): Multi-centre, double blind Randomized Controlled Trial comparing the efficacy of Diacetylmorphine vs. Hydromorphone for the treatment of long-term Injection Opiate Users who do not benefit from available therapies
FY 2008-09
Summary
Inner city populations, particularly injection drug users, are at
extremely high risk of many drug related harms including HIV,
hepatitis C and overdose death. While some treatments exist,
they are not optimal and people with the most severe cases of
heroin addiction remain outside of the health care system. To
improve the treatment of addiction, my colleagues and I are
conducting innovative clinical trials that are testing whether
medically prescribed heroin is a safe and effective treatment
that improves on currently available therapies. We are also
testing if pills can be used instead of injections and whether
licensed medications can be used instead of heroin. We will give
special attention to women and how they respond to the
treatments we are testing. The ultimate goal of this research is to
benefit both people with the most severe cases of heroin
addiction as well as their communities.
Department
Program
Randomized Controlled Trials
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
170813
Name
Krausz Reinhard M
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Clinical
Prcname2
Randomized Controlled Trials - B (RSB)
Projecttitle
Study to Assess Longer-term Opioid Medication Effectiveness (SALOME): Multi-centre, double blind Randomized Controlled Trial comparing the efficacy of Diacetylmorphine vs. Hydromorphone for the treatment of long-term Injection Opiate Users who do not benefit from available therapies
Programtype2
Randomized Controlled Trials
Orgnameinp2
University of British Columbia
Cihramount2
$999,997
Cihrequipment2
$0
Programname2
Randomized Controlled Trials
Keyworddelim
Maintenance Treatment; Opioid Dependence; Randomized Clinical Trial; Therapeutic Use Of Narcotics
Abstract
Inner city populations, particularly injection drug users, are at
extremely high risk of many drug related harms including HIV,
hepatitis C and overdose death. While some treatments exist,
they are not optimal and people with the most severe cases of
heroin addiction remain outside of the health care system. To
improve the treatment of addiction, my colleagues and I are
conducting innovative clinical trials that are testing whether
medically prescribed heroin is a safe and effective treatment
that improves on currently available therapies. We are also
testing if pills can be used instead of injections and whether
licensed medications can be used instead of heroin. We will give
special attention to women and how they respond to the
treatments we are testing. The ultimate goal of this research is to
benefit both people with the most severe cases of heroin
addiction as well as their communities.
Competitiondate
200809
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Krausz, Reinhard M; Oviedo-Joekes, Eugenia
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $999,997~ $0~
