Grant: Catalyst Grant: Pandemic Preparedness
Sunnybrook Research Institute (Toronto, Ontario)
$100,000.00
Understanding the role of host factors in human influenza virus transmission
FY 2009-10
Summary
Little is known about the nature of influenza virus transmission among humans. Resolution of this issue is essential for effective pandemic preparedness and reduction of annual disease. We hypothesize that host factors including intra-nasal colonization or lower respiratory tract infection with bacteria such as Staphylococcus aureus impact the efficiency of human influenza virus spread. The purpose of this research is to determine the importance of bacterial co-infection to the spread of influenza viruses. In order to accomplish this, studies will be conducted using a new animal model for the spread of human influenza virus.
Department
Program
Catalyst Grant: Pandemic Preparedness
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
183451
Name
Mubareka Samira
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Pandemic Preparedness
Projecttitle
Understanding the role of host factors in human influenza virus transmission
Programtype2
Operating Grants
Orgnameinp2
Sunnybrook Research Institute (Toronto, Ontario)
Cihramount2
$100,000
Cihrequipment2
$0
Programname2
Catalyst Grant: Pandemic Preparedness
Keyworddelim
Aerosols; Bacterial Proteases; Guinea Pigs; Influenza Virus; Staphylococcus Aureus; Transmission
Abstract
Little is known about the nature of influenza virus transmission among humans. Resolution of this issue is essential for effective pandemic preparedness and reduction of annual disease. We hypothesize that host factors including intra-nasal colonization or lower respiratory tract infection with bacteria such as Staphylococcus aureus impact the efficiency of human influenza virus spread. The purpose of this research is to determine the importance of bacterial co-infection to the spread of influenza viruses. In order to accomplish this, studies will be conducted using a new animal model for the spread of human influenza virus.
Competitiondate
200904
Approvedterm2
1 yr 0 mth
Pinamesdelim
Mubareka, Samira
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $100,000~ $0~
