Grant: Research Tools and Instruments - Category 1 (<$150,000)
York University
$80,701.00
Fast protein liquid chromatography (FPLC) system for the structural studies of the PHD finger proteins in yeast
FY 2009-10
Summary
Funds to purchase a Fast Protein Liquid Chromatography (FPLC) protein purification system are requested to aid the structural and functional studies of the yeast Plant Homeo-Domain (PHD) finger proteins led by the new investigator Dr. Yi Sheng at York University. The PHD finger proteins are small zinc-binding proteins, found to be involved in many important cellular processes such as gene regulation, immunity and development. The requested equipment will be used to purify yeast PHD finger proteins for three-dimensional structure determination and interaction studies with other cellular proteins. The outcome of this research will provide insight into the functional divergence of PHD finger proteins and reveal how mutations in these PHD finger affect cellular processes. The FPLC system is essential to the success of the proposed research.
Program
Research Tools and Instruments - Category 1 (<$150,000)
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
390710-2010
Name nom
Sheng, Yi
Department département
Biology
Organization id
38
Institution établissement
York University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2009
Competition year année de concours
2010
Award amount
80701
Program id
EQPEQ
Program nane en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1501
Committee name en
Genes, Cells and Molecules
Committee name fr
Gènes, cellules et molécules
Area of application code
1201
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Life sciences (including biotechnology)
Area of application fr
Sciences de la vie (y compris biotechnologie)
Research subject code
5403
Research subject group en
Biochemistry
Research subject group fr
Biochimie
Research subject en
Proteins and peptides, amino acids
Research subject fr
Protéines et peptides, acides aminés
Partie
1
Nb partie
1
Application title
Fast protein liquid chromatography (FPLC) system for the structural studies of the PHD finger proteins in yeast
Keyword
NA
Application summary
Funds to purchase a Fast Protein Liquid Chromatography (FPLC) protein purification system are requested to aid the structural and functional studies of the yeast Plant Homeo-Domain (PHD) finger proteins led by the new investigator Dr. Yi Sheng at York University. The PHD finger proteins are small zinc-binding proteins, found to be involved in many important cellular processes such as gene regulation, immunity and development. The requested equipment will be used to purify yeast PHD finger proteins for three-dimensional structure determination and interaction studies with other cellular proteins. The outcome of this research will provide insight into the functional divergence of PHD finger proteins and reveal how mutations in these PHD finger affect cellular processes. The FPLC system is essential to the success of the proposed research.
