Grant: Project Grant
University of Calgary
$546,975.00
Precision molecular diagnostics for crystal arthropathies
FY 2016-17
Summary
The formation of crystals of material in joints is a common feature of several types of arthritis, including gout, pseudo-gout, and inflammatory osteoarthritis. The current means to detect these crystals are not always accurate, which can lead to misdiagnosis and poor management of the condition. In the case of osteoarthritis, the crystals are so tiny that they often cannot be observed even with a microscope, which hampers both clinical diagnosis and research. The goal of this project is to develop peptide-based biosensors that will make the detection of these crystals easy and accurate. This project will provide physicians with improved tools to detect these crystals, leading to more accurate diagnoses, and improved patient outcomes.
Department
Program
Project Grant
Recipient
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
358080
Name
Maccallum Justin
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Musculoskeletal Health and Arthritis
Theme2
Biomedical
Prcname2
Project Grant Competition
Projecttitle
Precision molecular diagnostics for crystal arthropathies
Programtype2
Operating Grants
Orgnameinp2
University of Calgary
Cihramount2
$546,975
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Calcium Pyrophosphate Deposition Disease; Crystal Arhropathies; Diagnostics; Gout; Inflammatory Osteoarthritis; Microscopy; Phage Display; Psuedogout
Abstract
The formation of crystals of material in joints is a common feature of several types of arthritis, including gout, pseudo-gout, and inflammatory osteoarthritis. The current means to detect these crystals are not always accurate, which can lead to misdiagnosis and poor management of the condition. In the case of osteoarthritis, the crystals are so tiny that they often cannot be observed even with a microscope, which hampers both clinical diagnosis and research. The goal of this project is to develop peptide-based biosensors that will make the detection of these crystals easy and accurate. This project will provide physicians with improved tools to detect these crystals, leading to more accurate diagnoses, and improved patient outcomes.
Competitiondate
201610
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Maccallum, Justin
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $546,975~ $0~
