Grant: Project Grant
Université de Sherbrooke
$631,126.00
Impact in older adults of reducing anticholinergic and sedative medication burden on physical function measured by clinical digital phenotyping in lab and real-life environments
FY 2021-22
Summary
Some commonly used medications, such as medications for depression, allergies and sleep, have been found to decrease older adults' ability to move and walk. When this happens, older people may fall and need to be treated in hospital.
Previous studies have shown that these medications may cause people to become confused. They may also cause people to walk more slowly and take more time to stand up from a chair. These are considered the usual ways that people's ability to move around is measured in a study. Our project will look at these measurements when certain medications are stopped or the doses are lowered. Our project will also look at how technology like "smart" watches can measure the ability to move around. Using technology like smart watches can improve how to measure movement in research labs and at home. This study will also look at how stopping these medications affects how a person thinks and understands.
The research team includes different experts. The experts include pharmacists, an engineer, a kinesiologist (a human movement specialist), geriatricians, a physiotherapist, and a family physician. We believe the project will help answer several important questions, such as "Which groups of older adults benefit the most from decreasing or stopping potentially harmful medications?" and "How can we best measure changes in movement?" We also think that testing and confirming that smart watches accurately measure movement will help future studies. It will also be easier to study movement if people can wear a watch and not have to go into a research lab or only have to go for shorter periods of time.
Overall, the results of this study are important to assess how decreasing or stopping certain medications affect movement and how to best measure changes in movement.
Department
Program
Project Grant
Recipient
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
461661
Name
Cossette Benoît
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Aging
Theme2
Clinical
Prcname2
Biological and Clinical Aspects of Aging
Projecttitle
Impact in older adults of reducing anticholinergic and sedative medication burden on physical function measured by clinical digital phenotyping in lab and real-life environments
Programtype2
Operating Grants
Orgnameinp2
Université de Sherbrooke
Cihramount2
$631,126
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Anticholinergic Medications; Clinical Digital Phenotyping; Cognition; Deprescribing; Dual-Task Gait Assessment; Physical Function; Sedative Medications; Wearable Systems
Abstract
Some commonly used medications, such as medications for depression, allergies and sleep, have been found to decrease older adults' ability to move and walk. When this happens, older people may fall and need to be treated in hospital.
Previous studies have shown that these medications may cause people to become confused. They may also cause people to walk more slowly and take more time to stand up from a chair. These are considered the usual ways that people's ability to move around is measured in a study. Our project will look at these measurements when certain medications are stopped or the doses are lowered. Our project will also look at how technology like "smart" watches can measure the ability to move around. Using technology like smart watches can improve how to measure movement in research labs and at home. This study will also look at how stopping these medications affects how a person thinks and understands.
The research team includes different experts. The experts include pharmacists, an engineer, a kinesiologist (a human movement specialist), geriatricians, a physiotherapist, and a family physician. We believe the project will help answer several important questions, such as "Which groups of older adults benefit the most from decreasing or stopping potentially harmful medications?" and "How can we best measure changes in movement?" We also think that testing and confirming that smart watches accurately measure movement will help future studies. It will also be easier to study movement if people can wear a watch and not have to go into a research lab or only have to go for shorter periods of time.
Overall, the results of this study are important to assess how decreasing or stopping certain medications affect movement and how to best measure changes in movement.
Competitiondate
202203
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Cossette, Benoît; Boissy, Patrick; Lebel, Karina
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $631,126~ $0~