Grant: Operating Grant
University of Alberta
$730,948.00
Characterizing the epileptic network in epilepsy
FY 2010-11
Summary
Epilepsy is one of the most common neurologic disorders. While 75% of patients respond to medical therapy, the remainder often experience severe disability due to uncontrolled seizures. Magnetic Resonance Imaging (MRI)has recently demonstrated that structural abnormalities in patients with epilepsy are far more extensive than previously believed. How these structural abnormalities relate to the development of epilepsy, associated conditions such as memory impairement or depression and surgical outcome remains unknown. The purpose of this proposal is to characterize the anatomical abnormalities in epilepsy patients and to determine the relationship between anatomical abnormalities, seizures and associated conditions.
Department
Program
Operating Grant
Recipient
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
225565
Name
Gross Donald W
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Clinical
Prcname2
Systems & Circuits Neurosciences - A
Projecttitle
Characterizing the epileptic network in epilepsy
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$730,948
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Diffusion Tensor Imaging; Epilepsy; Histology; Idiopathic Generalized Epilepsy; Limbic System; Magnetization Transfer Ratio; Mesial Temporal Sclerosis; Myelin Water Fraction; Temporal Lobe Epilepsy; White Matter
Abstract
Epilepsy is one of the most common neurologic disorders. While 75% of patients respond to medical therapy, the remainder often experience severe disability due to uncontrolled seizures. Magnetic Resonance Imaging (MRI)has recently demonstrated that structural abnormalities in patients with epilepsy are far more extensive than previously believed. How these structural abnormalities relate to the development of epilepsy, associated conditions such as memory impairement or depression and surgical outcome remains unknown. The purpose of this proposal is to characterize the anatomical abnormalities in epilepsy patients and to determine the relationship between anatomical abnormalities, seizures and associated conditions.
Competitiondate
201103
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Gross, Donald W; Beaulieu, Christian
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $730,948~ $0~
