Grant: CIHR Fellowship
Direct Payment
$150,000.00
Uncovering the Oncogenic Drivers of Cancer Glycocalyx Remodeling Using Chemical-Genetic Screening
FY 2017-18
Summary
The surfaces of cancer cells are frequently coated with sugar molecules that help them to evade detection by the immune system. This research aims to discover the currently uncharacterized genetic changes within cancer cells that produce this modification of the cancer cell surface. In doing so we can identify ways of targeting cancer cells to make them more susceptible to detection and killing by the immune system, creating potential new approaches to treating cancer in patients.
Department
Program
CIHR Fellowship
Recipient
Location
California, United States of America
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
376169
Name
Wisnovsky Simon
Region
California
Country
United States of America
Orgtype
Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Fellowships - Post-PhD
Projecttitle
Uncovering the Oncogenic Drivers of Cancer Glycocalyx Remodeling Using Chemical-Genetic Screening
Programtype2
Fellowship Programs
Orgnameinp2
Direct Payment
Cihramount2
$150,000
Cihrequipment2
$0
Programname2
CIHR Fellowship
Keyworddelim
Cancer Immunology; Chemical Biology; Glycobiology
Abstract
The surfaces of cancer cells are frequently coated with sugar molecules that help them to evade detection by the immune system. This research aims to discover the currently uncharacterized genetic changes within cancer cells that produce this modification of the cancer cell surface. In doing so we can identify ways of targeting cancer cells to make them more susceptible to detection and killing by the immune system, creating potential new approaches to treating cancer in patients.
Competitiondate
201711
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Wisnovsky, Simon
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $150,000~ $0~
