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Grant: Project Grant

Unity Health Toronto

$657,901.00

Photoacoustics And Ultrasound for Acute Lung Injury (PAULI)

FY 2024-25

Summary
Much like the sensation of drowning, the lungs of ICU patients often are full of fluid due to infections like COVID-19. It is hard for doctors to know exactly how much fluid is present in the lungs without exposing the patients to harmful radiation doses. In this work, we propose to develop new approaches for monitoring this fluid buildup without using radiation, in a very easy-to-use manner. Our solution, named PAULI, involves ultrasound (US) and photoacoustic (PA) imaging, two techniques that can visualize lung damage through the use of harmless light and sound. We will validate their capabilities against the established standards, and allow doctors to easily monitor the progression of lung damage at the bedside.
Program
Project Grant
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
522687
Name
Hysi Eno
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Medical Physics & Imaging
Projecttitle
Photoacoustics And Ultrasound for Acute Lung Injury (PAULI)
Programtype2
Operating Grants
Orgnameinp2
Unity Health Toronto
Cihramount2
$657,901
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Acute Respiratory Distress Syndrome; Biomarker Validation; Computed Tomography; Functional And Structural; Lung Injuries; Non-Ionizing; Oxygenation; Perfusion; Photoacoustic Imaging; Ultrasound Imaging
Abstract
Much like the sensation of drowning, the lungs of ICU patients often are full of fluid due to infections like COVID-19. It is hard for doctors to know exactly how much fluid is present in the lungs without exposing the patients to harmful radiation doses. In this work, we propose to develop new approaches for monitoring this fluid buildup without using radiation, in a very easy-to-use manner. Our solution, named PAULI, involves ultrasound (US) and photoacoustic (PA) imaging, two techniques that can visualize lung damage through the use of harmless light and sound. We will validate their capabilities against the established standards, and allow doctors to easily monitor the progression of lung damage at the bedside.
Competitiondate
202503
Approvedterm2
4 yrs 0 mth
Pinamesdelim
Hysi, Eno; Lee, Warren L
Approvedterm
4 ans 0 mois
Cihrcontribution2
~ $657,901~ $0~
Unity Health Toronto - $657,901 Grant (2024-25) | Canada Spends