Grant: Operating Grant - PA: HIV/AIDS Research Initiative - Biomedical/Clinical Stream
University of Toronto
$416,638.00
Novel Small Molecule Modulators of HIV-1 RNA Processing
FY 2013-14
Summary
Although existing therapies are effective at controlling HIV-1 growth, the appearance of resistant strains of the virus call for additional approaches to control this infection. Our studies to date have identified a number of compounds that suppress virus growth by effecting a novel part of the virus life cycle not affected by current therapeutics. Research studies are outlined that would enhance our understanding of how these compounds work in an effort to enhance their antiviral activity while limiting their possible side effects.
Department
Program
Operating Grant - PA: HIV/AIDS Research Initiative - Biomedical/Clinical Stream
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
297384
Name
Cochrane Alan W
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Virology & Viral Pathogenesis
Projecttitle
Novel Small Molecule Modulators of HIV-1 RNA Processing
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$416,638
Cihrequipment2
$0
Programname2
Operating Grant - PA: HIV/AIDS Research Initiative - Biomedical/Clinical Stream
Keyworddelim
Hiv-1; Rna; Therapeutics
Abstract
Although existing therapies are effective at controlling HIV-1 growth, the appearance of resistant strains of the virus call for additional approaches to control this infection. Our studies to date have identified a number of compounds that suppress virus growth by effecting a novel part of the virus life cycle not affected by current therapeutics. Research studies are outlined that would enhance our understanding of how these compounds work in an effort to enhance their antiviral activity while limiting their possible side effects.
Competitiondate
201309
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Cochrane, Alan W
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $416,638~ $0~
