Grant: Canada Research Chairs
Concordia University
$200,000.00
Microbial Genomics
FY 2019-20
Summary
A fundamental question in biology is how gene expression can be controlled to permit cells with similar genomes to have very different behaviors. We propose to investigate how the similar genomes of the yeasts C. albicans and S. cerevisiae, can generate either a human pathogen causing potentially lethal infections in immunocompromised patients, or a highly beneficial industrial organism essential for making bread and wine. To do this we will map out the regulatory circuits in the pathogen C. albicans and compare them to the circuits already identified in the bakers yeast, and study how these differences have evolved.
Program
Canada Research Chairs
Recipient
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
1000228957-2012
Name nom
Whiteway, Malcolm
Department département
Department of Biology
Organization id
70
Institution établissement
Concordia University
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2019
Competition year année de concours
2012
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
5300
Research subject group en
Molecular biology
Research subject group fr
Biologie moléculaire
Research subject en
Molecular biology
Research subject fr
Biologie moléculaire
Installment
NA
Partie
0
Nb partie
NA
Application title
Microbial Genomics
Keyword
NSERC
Application summary
A fundamental question in biology is how gene expression can be controlled to permit cells with similar genomes to have very different behaviors. We propose to investigate how the similar genomes of the yeasts C. albicans and S. cerevisiae, can generate either a human pathogen causing potentially lethal infections in immunocompromised patients, or a highly beneficial industrial organism essential for making bread and wine. To do this we will map out the regulatory circuits in the pathogen C. albicans and compare them to the circuits already identified in the bakers yeast, and study how these differences have evolved.
