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Contribution: Industrial Research Assistance Program

MACH32 INC.

$80,000.00

Development of IMSAFE, an Intramuscular Autoinjector to Control Bleeding

FY 2025-26 · 2025-08-01

Summary
This project aims to develop a smaller, intramuscular autoinjector capable of delivering a concentrated formulation of tranexamic acid (TXA), a widely used antifibrinolytic for treating hemorrhage. The Firm’s current prototype can deliver up to 5 mL; however, user feedback from military and emergency responders indicates a strong preference for a more compact device. By formulating TXA at higher concentrations, the Firm has reduced the required injection volume to 2–3 mL. This enables the design of a smaller, more field-appropriate autoinjector without compromising therapeutic efficacy.
Program
Industrial Research Assistance Program
Recipient
Location
Edmonton|Edmonton, Alberta, Canada
Recipient Type
For-profit organization
Business Number
701428310
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions

Amendments

Each version of the agreement as published, oldest first, with its total as of that version. The amount above is the latest.

AmendmentDateFiscal YearTotal
02025-08-012025-26$80,000.00
12025-08-012025-26$80,000.00

As published

Additional Information
This agreement has been amended 1 time(s). The end date of this agreements has been modified by 91 days.
Additional Information (French)
Cet accord a été modifié 1 fois La date de fin du présent accord a été changé de 91 jours.
Agreement End Date
2026-06-30
Agreement Number
1033871
Agreement Start Date
2025-08-01
Agreement Title
Development of IMSAFE, an Intramuscular Autoinjector to Control Bleeding
Agreement Title (French)
Développement d’IMSAFE, un auto-injecteur intramusculaire pour contrôler les saignements
Agreement Type
Contribution
Agreement Value
$80,000.00
Amendment Date
2026-01-27
Amendment Number
1
Coverage
Industrial Research Assistance Program projects stimulate wealth creation for Canada through technological innovation and strengthen Canadian innovation ecosystem by creating new industrial capacity. | Les projets du Programme d'aide à la recherche industrielle favorisent la création de richesse au Canada grâce à l'innovation technologique et renforcent l'écosystème canadien de l'innovation en créant de nouvelles capacités industrielles.
Description
This project aims to develop a smaller, intramuscular autoinjector capable of delivering a concentrated formulation of tranexamic acid (TXA), a widely used antifibrinolytic for treating hemorrhage. The Firm’s current prototype can deliver up to 5 mL; however, user feedback from military and emergency responders indicates a strong preference for a more compact device. By formulating TXA at higher concentrations, the Firm has reduced the required injection volume to 2–3 mL. This enables the design of a smaller, more field-appropriate autoinjector without compromising therapeutic efficacy.
Description (French)
Ce projet vise à mettre au point un auto-injecteur intramusculaire plus petit, capable de délivrer une formulation concentrée d’acide tranexamique (TXA), un antifibrinolytique largement utilisé pour traiter les hémorragies. Le prototype actuel de l’entreprise peut délivrer jusqu’à 5 ml ; cependant, les commentaires des militaires et des intervenants d’urgence indiquent une forte préférence pour un dispositif plus compact. En formulant le TXA à des concentrations plus élevées, l’entreprise a réduit le volume d’injection nécessaire à 2 ou 3 ml. Cela permet de concevoir un auto-injecteur plus petit et mieux adapté au terrain sans compromettre l’efficacité thérapeutique.
Expected Results
The expected results and outcomes of NRC Industrial Research Assistance Program is focused on growing small and medium-sized enterprises (SMEs) through innovation and wealth creation for Canada.
Expected Results (French)
Les résultats attendus du Programme d’aide à la recherche industrielle du CNRC sont axés sur la croissance des petites et moyennes entreprises (PME) grâce à l’innovation et à la création de richesse pour le Canada.
Federal Riding
Edmonton--Wetaskiwin
Federal Riding (French)
Edmonton--Wetaskiwin
Federal Riding Number
48021
NAICS Code
334512
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program
Program Name (French)
Programme d’aide à la recherche industrielle
Program Purpose
The purpose of Industrial Research Assistance Program Contributions to Firms is to provide support that assists small and medium-sized enterprises (SMEs) to advance their innovation knowledge and ability to innovate, grow through innovation and stimulate wealth creation for Canada.
Program Purpose (French)
Les contributions versées aux entreprises en vertu du Programme d’aide à la recherche industrielle ont pour objectif d’apporter un soutien aux petites et moyennes entreprises (PME) afin qu’elles puissent approfondir leurs connaissances en matière d’innovation et renforcer leur capacité d’innovation, de croissance et de création de richesse pour le Canada.
Recipient Business Number
701428310
Recipient City
Edmonton|Edmonton
Recipient Country
CA
Recipient Legal Name
MACH32 INC.
Recipient Postal Code
T6X 0J6
Recipient Province or Territory
AB
Recipient Type
F
Reference Number
172-2025-2026-Q2-1033871
MACH32 INC. - $80,000 Contribution (2025-26) | Canada Spends