Grant: Operating Grant
University of British Columbia
$630,246.00
The Canadian STRIDER Trial: sildenafil for dismal prognosis IUGR.
FY 2013-14
Summary
In some pregnancies, the placenta (afterbirth) forms so poorly that the fetus cannot grow adequately and must be delivered too early to survive. We have preliminary data that suggest that using sildenafil citrate (the active drug in Viagra) may improve blood supply to placenta and help babies recover their growth to the point that they have an improved chance to survive. We will determine if growth does improve, and, then, in collaboration with colleagues undertaking similar smaller trials in other countries, have sufficient information to learn whether sildenafil will improve the chances of a baby surviving in a healthy state.
Department
Program
Operating Grant
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
303858
Name
Von Dadelszen Peter
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Human Development, Child and Youth Health
Theme2
Clinical
Prcname2
Clinical Investigation - A: Reproduction, Maternal, Child and Youth Health
Projecttitle
The Canadian STRIDER Trial: sildenafil for dismal prognosis IUGR.
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$630,246
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Fetal Growth; Intact Perinatal Survival; Intrauterine Growth Restriction; Placental Growth Factor; Randomised Controlled Trial; Sildenafil Citrate
Abstract
In some pregnancies, the placenta (afterbirth) forms so poorly that the fetus cannot grow adequately and must be delivered too early to survive. We have preliminary data that suggest that using sildenafil citrate (the active drug in Viagra) may improve blood supply to placenta and help babies recover their growth to the point that they have an improved chance to survive. We will determine if growth does improve, and, then, in collaboration with colleagues undertaking similar smaller trials in other countries, have sufficient information to learn whether sildenafil will improve the chances of a baby surviving in a healthy state.
Competitiondate
201403
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Von Dadelszen, Peter; Lim, Kenneth
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $630,246~ $0~
