Grant: Operating Grant
Memorial University of Newfoundland
$806,518.00
Finding the endocrine and genetic determinants of obesity: The Newfoundland study
FY 2008-09
Summary
Eating more than one needs is a major cause of human obesity. The gut produces chemicals called hormones that tell the brain how much we need to eat. If the level of these hormones is abnormal, one may eat too much leading to obesity. We think that one of the reasons why more people in Newfoundland are overweight/obese may be due to abnormal levels of these hormones. This abnormality may be genetic. We will study the role of genes in causing this abnormality in the Newfoundland population. We will measure food intake, total body fat, the level of gut hormones and relate these with any abnormality found in the genes we study. This information will help for development of medication to control abnormal gut hormone levels, food intake and obesity.
Department
Program
Operating Grant
Recipient
Location
Newfoundland and Labrador, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
172445
Name
Sun Guang
Region
Newfoundland and Labrador
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Biomedical
Prcname2
Nutrition, Food & Health
Projecttitle
Finding the endocrine and genetic determinants of obesity: The Newfoundland study
Programtype2
Operating Grants
Orgnameinp2
Memorial University of Newfoundland
Cihramount2
$806,518
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Cck; Food Intake And Macronutrients; Genetically Homogeneous Newfoundland Population; Ghrelin; Gut Hormones; Ppy And Pyy3-36; Snps; Willett Food Frequency Questionnaire
Abstract
Eating more than one needs is a major cause of human obesity. The gut produces chemicals called hormones that tell the brain how much we need to eat. If the level of these hormones is abnormal, one may eat too much leading to obesity. We think that one of the reasons why more people in Newfoundland are overweight/obese may be due to abnormal levels of these hormones. This abnormality may be genetic. We will study the role of genes in causing this abnormality in the Newfoundland population. We will measure food intake, total body fat, the level of gut hormones and relate these with any abnormality found in the genes we study. This information will help for development of medication to control abnormal gut hormone levels, food intake and obesity.
Competitiondate
200809
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Sun, Guang
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $806,518~ $0~
